6-((Benzyloxy)carbonyl)-6-azaspiro[2.5]octane-1-carboxylic acid

Base Information

Chemical Name:6-((Benzyloxy)carbonyl)-6-azaspiro[2.5]octane-1-carboxylic acid
CAS No.:147610-85-3
Molecular Formula:C16H19NO4
Molecular Weight:289.331
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80682161
Mol file:147610-85-3.mol

Synonyms:147610-85-3;6-((Benzyloxy)carbonyl)-6-azaspiro[2.5]octane-1-carboxylic acid;6-(Benzyloxycarbonyl)-6-azaspiro[2.5]octane-1-carboxylic acid;6-[(benzyloxy)carbonyl]-6-azaspiro[2.5]octane-1-carboxylic acid;6-Aza-spiro[2.5]octane-1,6-dicarboxylic acid 6-benzyl ester;6-phenylmethoxycarbonyl-6-azaspiro[2.5]octane-2-carboxylic acid;SCHEMBL2798935;DTXSID80682161;XFA61085;MFCD17214280;AKOS015839352;PB22887;AS-43191;CS-0050359;EN300-255551;A884419;6-CBZ-6-AZASPIRO[2.5]OCTANE-1-CARBOXYLIC ACID;(R)-6-(benzyloxycarbonyl)-6-azaspiro(2.5)octane-1-carboxylic;6-((Benzyloxy)carbonyl)-6-azaspiro[2.5]octane-1-carboxylicacid

Suppliers and Price of 6-((Benzyloxy)carbonyl)-6-azaspiro[2.5]octane-1-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-(Benzyloxycarbonyl)-6-azaspiro[2.5]octane-1-carboxylicacid
25mg
$ 70.00

Synthonix
6-Cbz-6-azaspiro[2.5]octane-1-carboxylicacid 95+%
5g
$ 500.00

SynQuest Laboratories
6-[(Benzyloxy)carbonyl]-6-azaspiro[2.5]octane-1-carboxylic acid 97.0%
250 mg
$ 290.00

SynQuest Laboratories
6-[(Benzyloxy)carbonyl]-6-azaspiro[2.5]octane-1-carboxylic acid 97.0%
1 g
$ 790.00

J&W Pharmlab
6-Aza-spiro[2.5]octane-1,6-dicarboxylicacid6-benzylester 98%
5g
$ 2390.00

J&W Pharmlab
6-Aza-spiro[2.5]octane-1,6-dicarboxylicacid6-benzylester 98%
1g
$ 598.00

J&W Pharmlab
6-Aza-spiro[2.5]octane-1,6-dicarboxylicacid6-benzylester 98%
500mg
$ 349.00

Crysdot
6-((Benzyloxy)carbonyl)-6-azaspiro[2.5]octane-1-carboxylicacid 95+%
1g
$ 375.00

Chemenu
6-((benzyloxy)carbonyl)-6-azaspiro[2.5]octane-1-carboxylicacid 95%
1g
$ 351.00

Ambeed
6-((Benzyloxy)carbonyl)-6-azaspiro[2.5]octane-1-carboxylicacid 96%
5g
$ 548.00

Total 15 raw suppliers

Chemical Property of 6-((Benzyloxy)carbonyl)-6-azaspiro[2.5]octane-1-carboxylic acid

Chemical Property:

Boiling Point:479.2±45.0 °C(Predicted)
PKA:4.71±0.20(Predicted)
PSA：66.84000
Density:1.30±0.1 g/cm3(Predicted)
LogP:2.44780
Storage Temp.:Room temperature.
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:289.13140809
Heavy Atom Count:21
Complexity:409

Purity/Quality:

97% ^*data from raw suppliers

6-(Benzyloxycarbonyl)-6-azaspiro[2.5]octane-1-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCC12CC2C(=O)O)C(=O)OCC3=CC=CC=C3

Technology Process of 6-((Benzyloxy)carbonyl)-6-azaspiro[2.5]octane-1-carboxylic acid

There total 5 articles about 6-((Benzyloxy)carbonyl)-6-azaspiro[2.5]octane-1-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 147610-84-2
6-benzyl 1-ethyl 6-azaspiro[2.5]octane-1,6-dicarboxylate

: 147610-85-3
6-(benzyloxycarbonyl)-6-azaspiro[2.5]octane-1-carboxylic acid

Guidance literature:: 6-benzyl 1-ethyl 6-azaspiro[2.5]octane-1,6-dicarboxylate; With sodium hydroxide; water; In methanol; at 18 - 25 ℃; for 2h; Heating / reflux;

With hydrogenchloride; In water; ethyl acetate; Product distribution / selectivity;

Reference yield: 99.0%

: 1419221-95-6
6-benzyl 1-methyl 6-azaspiro[2.5]octane-1,6-dicarboxylate

: 147610-85-3
6-(benzyloxycarbonyl)-6-azaspiro[2.5]octane-1-carboxylic acid

Guidance literature:: 6-benzyl 1-methyl 6-azaspiro[2.5]octane-1,6-dicarboxylate; With lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 17h;

With hydrogenchloride; In water; pH=3 - 4;