1-(3-Chlorophenyl)-2-phenylethyne

Base Information

• Chemical Name: 1-(3-Chlorophenyl)-2-phenylethyne
• CAS No.: 51624-34-1
• Molecular Formula: C14H9Cl
• Molecular Weight: 212.678
• Hs Code.: 2903999090
• Mol file: 51624-34-1.mol

Synonyms:1-(3-Chlorophenyl)-2-phenylethyne;1-(Phenylethynyl)-3-chlorobenzene;1-Chloro-3-(phenylethynyl)benzene;1-Phenyl-2-(3-chlorophenyl)acetylene;1-Phenyl-2-(3-chlorophenyl)ethyne;1-Chloro-3-(2-phenylethynyl)benzene

Chemical Property of 1-(3-Chlorophenyl)-2-phenylethyne

Chemical Property:

• PSA: 0.00000
• LogP: 3.73980

Purity/Quality:

97% ^*data from raw suppliers

1-Chloro-3-phenylethynyl-benzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(3-Chlorophenyl)-2-phenylethyne

There total 29 articles about 1-(3-Chlorophenyl)-2-phenylethyne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-iodochlorobenzene (625-99-0) + phenylacetylene (536-74-3) → 1-chloro-3-(2-phenylethynyl)benzene (51624-34-1)

Guidance literature:

With palladium diacetate; potassium carbonate; In ethanol; at 80 ℃; for 24h;

DOI:10.1021/acscatal.9b04593

Reference yield: 99.0%

iodobenzene (591-50-4) + m-chlorophenylacetylene (766-83-6) → 1-chloro-3-(2-phenylethynyl)benzene (51624-34-1)

Guidance literature:

With CuI(xantphos); caesium carbonate; In N,N-dimethyl-formamide; at 135 ℃; for 0.166667h; Inert atmosphere; Microwave irradiation;

DOI:10.1055/s-0031-1290813

Reference yield: 89.0%

3-chlorophenylboronic acid (63503-60-6) + 1-Bromo-2-phenylacetylene (932-87-6) → 1-chloro-3-(2-phenylethynyl)benzene (51624-34-1)

Guidance literature:

With potassium phosphate; diethylzinc; N,N`-dimethylethylenediamine; In tetrahydrofuran; at 80 ℃; for 48h; Molecular sieve; Inert atmosphere;

DOI:10.1016/j.jcat.2019.03.005

upstream raw materials:

3-chloro-benzil-dihydrazone

copper(I) phenylacetylenide

3-iodochlorobenzene

phenylacetylene

Downstream raw materials:

ethyl 2-(3-chlorophenyl)-3-phenylcycloprop-2-ene-1-carboxylate

(Z)-1-chloro-3-styrylbenzene

(E)-3-chlorostilbene

3-chlorobenzophenone