(4aS,6aR,6bS,12aS,14aR,14bR,Z)-Methyl 11-(hydroxyMethylene)-2,2,6a,6b,9,9,12a-heptaMethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4a-carboxylate

Base Information

Chemical Name:(4aS,6aR,6bS,12aS,14aR,14bR,Z)-Methyl 11-(hydroxyMethylene)-2,2,6a,6b,9,9,12a-heptaMethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4a-carboxylate
CAS No.:305818-39-7
Molecular Formula:C32H46O5
Molecular Weight:510.714
Hs Code.:
Mol file:305818-39-7.mol

(4aS,6aR,6bS,12aS,14aR,14bR,Z)-Methyl 11-(hydroxyMethylene)-2,2,6a,6b,9,9,12a-heptaMethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4a-carboxylate

Synonyms:(4aS,6aR,6bS,12aS,14aR,14bR,Z)-Methyl 11-(hydroxyMethylene)-2,2,6a,6b,9,9,12a-heptaMethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4a-carboxylate

Suppliers and Price of (4aS,6aR,6bS,12aS,14aR,14bR,Z)-Methyl 11-(hydroxyMethylene)-2,2,6a,6b,9,9,12a-heptaMethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4a-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (4aS,6aR,6bS,12aS,14aR,14bR,Z)-Methyl 11-(hydroxyMethylene)-2,2,6a,6b,9,9,12a-heptaMethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4a-carboxylate

Chemical Property:

Boiling Point:599.8±50.0 °C(Predicted)
PKA:4.50±1.00(Predicted)
PSA：80.67000
Density:1.15±0.1 g/cm3(Predicted)
LogP:6.76100

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (4aS,6aR,6bS,12aS,14aR,14bR,Z)-Methyl 11-(hydroxyMethylene)-2,2,6a,6b,9,9,12a-heptaMethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4a-carboxylate

There total 3 articles about (4aS,6aR,6bS,12aS,14aR,14bR,Z)-Methyl 11-(hydroxyMethylene)-2,2,6a,6b,9,9,12a-heptaMethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4a-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 218600-50-1
methyl 3,12-dioxoolean-9⁽¹¹⁾-en-28-oate

: 109-94-4
formic acid ethyl ester

: 305818-39-7
methyl 2-hydroxymethylene-3,12-dioxoolean-9⁽¹¹⁾-en-28-oate

Guidance literature:: With sodium methylate; In benzene; at 20 ℃; for 2h;
DOI:10.1021/jm0002230

Reference yield:

: 65023-19-0
methyl 3β-hydroxy-12-oxoolean-9(11)-en-28-oate

: 305818-39-7
methyl 2-hydroxymethylene-3,12-dioxoolean-9⁽¹¹⁾-en-28-oate

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / Jones reagent / acetone / 0.17 h / 20 °C

2: 99 percent / NaOMe / benzene / 2 h / 20 °C

With jones reagent; sodium methylate; In acetone; benzene; 1: Jones oxidation;
DOI:10.1021/jm0002230

Reference yield:

: 65023-20-3
methyl 3β-acetoxy-12-oxoolean-9(11)-en-28-oate

: 305818-39-7
methyl 2-hydroxymethylene-3,12-dioxoolean-9⁽¹¹⁾-en-28-oate

Guidance literature:: Multi-step reaction with 3 steps

1: 97 percent / methanolic KOH / 0.5 h / Heating

2: 92 percent / Jones reagent / acetone / 0.17 h / 20 °C

3: 99 percent / NaOMe / benzene / 2 h / 20 °C

With potassium hydroxide; jones reagent; sodium methylate; In acetone; benzene; 2: Jones oxidation;
DOI:10.1021/jm0002230