4,4-Dimethylpimelic acid diethyl ester

Base Information

• Chemical Name: 4,4-Dimethylpimelic acid diethyl ester
• CAS No.: 55134-05-9
• Molecular Formula: C₁₃H₂₄O₄
• Molecular Weight: 244.331
• Hs Code.: 2917190090
• Mol file: 55134-05-9.mol

Synonyms:4,4-Dimethylheptanedioic acid diethyl ester;4,4-Dimethylpimelic acid diethyl ester

Chemical Property of 4,4-Dimethylpimelic acid diethyl ester

Chemical Property:

• Boiling Point: 135 °C(Press: 7 Torr)
• PSA: 52.60000
• Density: 0.9732 g/cm3
• LogP: 2.69920

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,4-Dimethylpimelic acid diethyl ester

There total 6 articles about 4,4-Dimethylpimelic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,3-dimethylpent-1,5-diol (53120-74-4) → 4,4-dimethyl-heptanedioic acid diethyl ester (55134-05-9)

Guidance literature:

Multi-step reaction with 3 steps

1: SOCl₂

3: concentrated H₂SO₄

With thionyl chloride; sulfuric acid;

DOI:10.1021/ja01296a031

Reference yield:

1,5-dichloro-3,3-dimethyl-pentane (62496-53-1) → 4,4-dimethyl-heptanedioic acid diethyl ester (55134-05-9)

Guidance literature:

Multi-step reaction with 2 steps

2: concentrated H₂SO₄

With sulfuric acid;

DOI:10.1021/ja01296a031

Reference yield:

3,3-Dimethylglutaric acid (4839-46-7) → 4,4-dimethyl-heptanedioic acid diethyl ester (55134-05-9)

Guidance literature:

Multi-step reaction with 4 steps

1: copper chromite / 183877 Torr / Hydrogenation

2: SOCl₂

4: concentrated H₂SO₄

With thionyl chloride; copper chromite; sulfuric acid;

DOI:10.1021/ja01296a031

upstream raw materials:

ethanol

4,4-dimethylheptanedinitrile

4,4-dimethyl-1,7-heptanedioic acid

3,3-dimethylpent-1,5-diol

Downstream raw materials:

8,8-dimethyl-2-oxa-spiro[4.5]decane-1,3-dione

cyano-(4,4-dimethyl-cyclohexyliden)-acetic acid ethyl ester

(1-carboxy-4,4-dimethyl-cyclohexyl)-acetic acid

4,4-dimethylcyclohexane-1-one