3-(3,4-DIMETHYLPHENYL)PROPIOPHENONE

Base Information

• Chemical Name: 3-(3,4-DIMETHYLPHENYL)PROPIOPHENONE
• CAS No.: 898755-52-7
• Molecular Formula: C₁₇H₁₈O
• Molecular Weight: 238.329
• Hs Code.: 2914399090
• Mol file: 898755-52-7.mol

Synonyms:3-(3,4-DIMETHYLPHENYL)PROPIOPHENONE

Chemical Property of 3-(3,4-DIMETHYLPHENYL)PROPIOPHENONE

Chemical Property:

• Vapor Pressure: 3.32E-06mmHg at 25°C
• Boiling Point: 387.3°C at 760 mmHg
• Flash Point: 168.4°C
• PSA: 17.07000
• Density: 1.032g/cm³
• LogP: 4.11890

Purity/Quality:

97% ^*data from raw suppliers

3-(3,4-dimethylphenyl)propiophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(3,4-DIMETHYLPHENYL)PROPIOPHENONE

There total 4 articles about 3-(3,4-DIMETHYLPHENYL)PROPIOPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

3,4-dimethylbenzyl alcohol (6966-10-5) + phenylacetylene (536-74-3) → 3-(3,4-dimethylphenyl)-1-phenylpropan-1-one (898755-52-7)

Guidance literature:

phenylacetylene; With chloro(1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene)gold(I); water; silver trifluoromethanesulfonate; In 1,4-dioxane; at 120 ℃; for 1h; Microwave irradiation;

3,4-dimethylbenzyl alcohol; With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; potassium tert-butylate; In 1,4-dioxane; at 130 ℃; for 2h; Microwave irradiation;

Reference yield: 85.0%

1-Phenylethanol (98-85-1,13323-81-4) + 3,4-dimethylbenzyl alcohol (6966-10-5) → 3-(3,4-dimethylphenyl)-1-phenylpropan-1-one (898755-52-7)

Guidance literature:

1-Phenylethanol; With Cp*Ir(6,6'-dionato-2,2'-bipyridine)(H₂O); In tert-Amyl alcohol; at 20 ℃; for 6h; Reflux;

3,4-dimethylbenzyl alcohol; With caesium carbonate; In tert-Amyl alcohol; for 6h; Reflux;

Reference yield: 85.0%

3,4-dimethylbenzyl alcohol (6966-10-5) + acetophenone (98-86-2) → 3-(3,4-dimethylphenyl)-1-phenylpropan-1-one (898755-52-7)

Guidance literature:

With Cp*Ir(6,6'-dionato-2,2'-bipyridine)(H₂O); caesium carbonate; In tert-Amyl alcohol; for 6h; Reflux;

DOI:10.1021/acs.joc.5b01975

upstream raw materials:

1-Phenylethanol

3,4-dimethylbenzyl alcohol

acetophenone

phenylacetylene

Refernces

• 1、 -. "A method for synthesis of α-alkyl ketone". Paragraph 0036; 0037; 0038; 0039. . Retrieved 2016/11/28.