4-(4-FLUOROPHENYL)-1-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID ETHYL ESTER

Base Information

Chemical Name:4-(4-FLUOROPHENYL)-1-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID ETHYL ESTER
CAS No.:191668-18-5
Molecular Formula:C14H14FNO2
Molecular Weight:0
Hs Code.:
Mol file:191668-18-5.mol

Synonyms:4-(4-FLUOROPHENYL)-1-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID ETHYL ESTER

Suppliers and Price of 4-(4-FLUOROPHENYL)-1-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID ETHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 4-(4-FLUOROPHENYL)-1-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID ETHYL ESTER

Chemical Property:

PSA：31.23000
LogP:3.00790

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(4-FLUOROPHENYL)-1-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID ETHYL ESTER

There total 2 articles about 4-(4-FLUOROPHENYL)-1-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 191668-10-7
ethyl 4-(4-fluorophenyl)-1H-pyrrole-3-carboxylate

: 74-88-4
methyl iodide

: 191668-18-5
4-(4-fluoro-phenyl)-1-methyl-1H-pyrrole-3-carboxylic acid ethyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 90 ℃; for 15h;

Reference yield:

: 136265-10-6,352-03-4,24393-50-8
ethyl 4-fluorocinnamate

: 191668-18-5
4-(4-fluoro-phenyl)-1-methyl-1H-pyrrole-3-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / 60 percent sodium hydride in oil / dimethylsulfoxide; diethyl ether / 0.08 h / 20 °C

2: 69 percent / potassium carbonate / dimethylformamide / 15 h / 90 °C

With sodium hydride; potassium carbonate; In diethyl ether; dimethyl sulfoxide; N,N-dimethyl-formamide; 1: Cycloaddition / 2: Methylation;