Vorapaxar

Base Information

Chemical Name:Vorapaxar
CAS No.:900161-12-8
Molecular Formula:C29H34N2O5
Molecular Weight:490.599
Hs Code.:

Synonyms:[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(Diphenylamino)carbonyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]carbamic acid ethyl ester;ethyl((1R,3aR,4aR,6R,8aR,9S,9aS)-9-(diphenylcarbamoyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamate;ethyl(1R,3aR,4aR,6R,8aS,9S,9aS)-9-(diphenylcarbamoyl)-1,4a-dimethyl-3-oxododecahydroaphtho[2,3-c]furan-6-ylcarbamate

Suppliers and Price of Vorapaxar

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
[(1R,?3aR,?4aR,?6R,?8aR,?9S,?9aS)?-?9-?[(Diphenylamino)?carbonyl]?dodecahydro-?1-?methyl-?3-?oxonaphtho[2,?3-?c]?furan-?6-?yl]?-?carbamicAcidEthylEster
500mg
$ 1255.00

Crysdot
Ethyl((1R,3aR,4aR,6R,8aR,9S,9aS)-9-(diphenylcarbamoyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamate 97%
1g
$ 680.00

Chemenu
ethyl((1R,3aR,4aR,6R,8aR,9S,9aS)-9-(diphenylcarbamoyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamate 97%
1g
$ 636.00

Total 60 raw suppliers

Chemical Property of Vorapaxar

Chemical Property:

Boiling Point:733.5±60.0 °C(Predicted)
PKA:12.42±0.60(Predicted)
PSA：84.94000
Density:1.25±0.1 g/cm3(Predicted)
LogP:5.47080

Purity/Quality:

99%, ^*data from raw suppliers

[(1R,?3aR,?4aR,?6R,?8aR,?9S,?9aS)?-?9-?[(Diphenylamino)?carbonyl]?dodecahydro-?1-?methyl-?3-?oxonaphtho[2,?3-?c]?furan-?6-?yl]?-?carbamicAcidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses [(1R,?3aR,?4aR,?6R,?8aR,?9S,?9aS)?-?9-?[(Diphenylamino)?carbonyl]?dodecahydro-?1-?methyl-?3-?oxonaphtho[2,?3-?c]?furan-?6-?yl]?-?carbamic Acid Ethyl Ester is a related compound of Himbacine (H456343), an alkaloid muscarinic receptor antagonist.

Technology Process of Vorapaxar

There total 21 articles about Vorapaxar which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.1%

: 900161-11-7
C₂₉H₃₂N₂O₅

: 900161-12-8
C₂₉H₃₄N₂O₅

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 30 ℃; for 16h; under 3800.26 Torr;

Reference yield: 85.0%

: 900186-76-7
C₂₆H₃₀N₂O₃

: 541-41-3
chloroformic acid ethyl ester

: 900161-12-8
C₂₉H₃₄N₂O₅

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 - 20 ℃; for 0.5h; Product distribution / selectivity;

Reference yield:

: 541-41-3
chloroformic acid ethyl ester

: 900161-12-8
C₂₉H₃₄N₂O₅

Guidance literature:: C₂₆H₃₀N₂O₃; With sodium hydroxide; In tetrahydrofuran; water; at 10 ℃; pH=9;

chloroformic acid ethyl ester; With triethylamine; In tetrahydrofuran; at 5 - 20 ℃; for 0.5h;