900161-11-7 Usage
General Description
Vorapaxar sulfate M-9 is a chemical compound that belongs to the class of vorapaxar, a potent and selective antagonist of the protease-activated receptor-1 (PAR-1). PAR-1 is a key receptor involved in platelet activation and aggregation, and therefore, vorapaxar sulfate M-9 is used as an antiplatelet medication to prevent blood clot formation in patients with a history of myocardial infarction or peripheral arterial disease. It works by inhibiting the binding of thrombin to PAR-1, thereby reducing platelet activation and aggregation. Vorapaxar sulfate M-9 has shown efficacy in reducing the risk of cardiovascular events, such as heart attack and stroke, in clinical trials and is considered a valuable therapeutic option in the management of cardiovascular diseases. However, it should be used with caution in patients at risk of bleeding complications.
Check Digit Verification of cas no
The CAS Registry Mumber 900161-11-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,0,1,6 and 1 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 900161-11:
(8*9)+(7*0)+(6*0)+(5*1)+(4*6)+(3*1)+(2*1)+(1*1)=107
107 % 10 = 7
So 900161-11-7 is a valid CAS Registry Number.
900161-11-7Relevant articles and documents
Vorapaxar intermediate and preparation method thereof
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, (2020/05/14)
The invention relates to an anticoagulant vorapaxar intermediate compound and a preparation method thereof. The preparation method specifically comprises that a completely-new oxime-based compound B is used as a starting compound, a five-step reaction is performed to synthesize the key amide intermediate G of vorapaxar, and through the intermediate, vorapaxar and the analog thereof can be furtherconveniently synthesized. According to the present invention, the use of the high-polarity and high-boiling-point solvent is avoided, the too-low-temperature operation and the too-high-temperature operation are avoided, and the method has characteristics of simpleness, easy performing and low production cost, and is suitable for industrial production. The specific route is defined in the specification.
Vorapaxar intermediate and preparation method thereof
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, (2017/07/13)
The invention discloses a vorapaxar intermediate and a preparation method thereof. The invention provides the preparation method of the vorapaxar intermediate I, wherein the preparation method comprises the following steps: in a closed system, and under c
