3-AMinocyclopentanecarboxylic acid hydrochloride

Base Information

• Chemical Name: 3-AMinocyclopentanecarboxylic acid hydrochloride
• CAS No.: 1203306-05-1
• Molecular Formula: C6H12ClNO2
• Molecular Weight: 165.61798
• Mol file: 1203306-05-1.mol

Synonyms:3-AMinocyclopentanecarboxylic acid hydrochloride;Cyclopentanecarboxylic acid, 3-aMino-, hydrochloride;3-aminocyclopentane-1-carboxylic acid hydrochloride

Chemical Property of 3-AMinocyclopentanecarboxylic acid hydrochloride

Chemical Property:

• PSA: 63.32000
• LogP: 1.70070
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

3-AminocyclopentanecarboxylicAcidHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-AMinocyclopentanecarboxylic acid hydrochloride

There total 19 articles about 3-AMinocyclopentanecarboxylic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(1R,3R)-3-((tert-butoxycarbonyl)amino)cyclopentane-1-carboxylic acid (489446-85-7) → (1R,3R)-3-aminocyclopentane-1-carboxylic acid hydrochloride (1203306-05-1,1392803-15-4,19042-35-4,147780-44-7)

Guidance literature:

(1R,3R)-3-((tert-butoxycarbonyl)amino)cyclopentane-1-carboxylic acid; In dichloromethane; at 20 ℃; for 2h;

With hydrogenchloride; In 1,4-dioxane;

Reference yield: 93.0%

2-Azabicyclo[2.2.1]heptan-3-one (24647-29-8) → cis-3-aminocyclopentanecarboxylic acid hydrochloride (1203306-05-1,1392803-15-4,19042-35-4,147780-44-7)

Guidance literature:

With hydrogenchloride; at 20 ℃; for 48h;

DOI:10.1002/anie.200501555

Reference yield: 87.2%

1-azabicyclo[2.2.1]heptan-3-one (21472-89-9) → (1S,3R)-3-aminocyclopentanecarboxylic acid hydrochloride salt (1203306-05-1,1392803-15-4,19042-35-4,147780-44-7)

Guidance literature:

With hydrogenchloride; for 4h; Reflux;

upstream raw materials:

(1S,4R)-N-(9-Phenylfluoren-9-yl)-2-azabicyclo<2.2.1>heptan-3-one

(-)-2-Azabicyclo<2.2.1>heptan-3-one

1-azabicyclo[2.2.1]heptan-3-one

(1S,3R)-3-(tert-butoxycarbonylamino)cyclopentanecarboxylic acid

Downstream raw materials:

(1R,3S)-methyl 3-aminocyclopentanecarboxylate hydrochloride

(1R,3S)-3-((tert-butoxycarbonyl)amino)cyclopentane-1-carboxylic acid

(1S,3R)-3-(tert-butoxycarbonylamino)cyclopentanecarboxylic acid