N-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl]formamide

Base Information

Chemical Name:N-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl]formamide
CAS No.:109912-29-0
Molecular Formula:C16H19N3O2
Molecular Weight:285.34
Hs Code.:
DSSTox Substance ID:DTXSID80399444
Mol file:109912-29-0.mol

Synonyms:109912-29-0;N-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl]formamide;N'-FORMYL-N-(4-METHOXYBENZYL)-N-(2-PYRIDINYL)-1,2-ETHANEDIAMINE;N-(2-{[(4-Methoxyphenyl)methyl](pyridin-2-yl)amino}ethyl)formamide;N'-Formyl-N-(4-methoxybenzyl)-N-2-pyridinyl-1,2-ethanediamine;DTXSID80399444;XFUREOITKIFVPB-UHFFFAOYSA-N;FT-0668841;N inverted exclamation mark -Formyl-N-(4-methoxybenzyl)-N-(2-pyridinyl)-1,2-ethanediamine

Suppliers and Price of N-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl]formamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N'-FORMYL-N-(4-METHOXYBENZYL)-N-2-PYRIDINYL-1,2-ETHANEDIAMINE 95.00%
5MG
$ 500.32

Total 3 raw suppliers

Chemical Property of N-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl]formamide

Chemical Property:

Boiling Point:527.9±45.0 °C(Predicted)
PKA:15.65±0.23(Predicted)
PSA：57.95000
Density:1.167±0.06 g/cm3(Predicted)
LogP:2.68310
Solubility.:Chloroform, Dichloromethane, Methanol
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:285.147726857
Heavy Atom Count:21
Complexity:293

Purity/Quality:

95% ^*data from raw suppliers

N'-FORMYL-N-(4-METHOXYBENZYL)-N-2-PYRIDINYL-1,2-ETHANEDIAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CN(CCNC=O)C2=CC=CC=N2
Uses Iodobolpyramine derivative as ligand for detecting histamine H1 receptors.

Technology Process of N-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl]formamide

There total 2 articles about N-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl]formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 109-04-6
2-bromo-pyridine

: 109912-29-0
N'-formyl-N-(4-methoxybenzyl)-N-2-pyridinyl-1,2-ethanediamine

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / pyridine / 5 h / Heating

2: 71 percent / sodium hydride / dimethylsulfoxide / 1.) below 40 deg C, 20 min, 2.) 22 deg C, 45 min

3: 91 percent / acetic anhydride / diethyl ether / 16 h / 22 °C

With acetic anhydride; sodium hydride; In pyridine; diethyl ether; dimethyl sulfoxide;
DOI:10.1016/0223-5234(87)90002-X

Reference yield:

: 74764-17-3
2-[(pyridin-2-yl)amino]ethylamine

: 109912-29-0
N'-formyl-N-(4-methoxybenzyl)-N-2-pyridinyl-1,2-ethanediamine

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / sodium hydride / dimethylsulfoxide / 1.) below 40 deg C, 20 min, 2.) 22 deg C, 45 min

2: 91 percent / acetic anhydride / diethyl ether / 16 h / 22 °C

With acetic anhydride; sodium hydride; In diethyl ether; dimethyl sulfoxide;
DOI:10.1016/0223-5234(87)90002-X