1,8-dimethyl-3,6-diazatricyclo[4.3.1.1~3,8~]undecan-9-one

Base Information

• Chemical Name: 1,8-dimethyl-3,6-diazatricyclo[4.3.1.1~3,8~]undecan-9-one
• CAS No.: 123366-49-4
• Molecular Formula: C11H18N2O
• Molecular Weight: 194.27
• Hs Code.: 2933990090
• Mol file: 123366-49-4.mol

Synonyms:1,8-dimethyl-3,6-diazatricyclo[4.3.1.1~3,8~]undecan-9-one;1,8-dimethyl-3,6-diazatricyclo[4.3.1.1~3,8~]undecan-9-one(SALTDATA: FREE)

Chemical Property of 1,8-dimethyl-3,6-diazatricyclo[4.3.1.1~3,8~]undecan-9-one

Chemical Property:

• Vapor Pressure: 0.00181mmHg at 25°C
• Boiling Point: 292.7°C at 760 mmHg
• Flash Point: 120.6°C
• PSA: 23.55000
• Density: 1.17g/cm³
• LogP: 0.08870

Purity/Quality:

99% ^*data from raw suppliers

1,8-Dimethyl-3,6-diazatricyclo[4.3.1.1~3,8~]undecan-9-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,8-dimethyl-3,6-diazatricyclo[4.3.1.1~3,8~]undecan-9-one

There total 2 articles about 1,8-dimethyl-3,6-diazatricyclo[4.3.1.1~3,8~]undecan-9-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

1,3,6,8-tetraazatricyclo[4.4.1.13,8]dodecane (51-46-7) + pentan-3-one (96-22-0) → 6,8-dimethyl-7-oxo-diazatricyclo<4.3.1.13,8>undecane (123366-49-4)

Guidance literature:

With acetic acid; In isopropyl alcohol; for 1h; Heating;

DOI:10.1007/BF00487436

Reference yield:

5,7-Dimethyl-6-oxo-1,3-diazaadamantane (80808-86-2) + ethylene dibromide (106-93-4) → 6,8-dimethyl-7-oxo-diazatricyclo<4.3.1.13,8>undecane (123366-49-4)

Guidance literature:

With triethylamine; Yield given. Multistep reaction; 1.) benzene, reflux, 1 h, 2.) benzene, reflux, 8 h;

DOI:10.1007/BF00531328

Reference yield: 68.0%

bromobenzene (108-86-1,52753-63-6) + 6,8-dimethyl-7-oxo-diazatricyclo<4.3.1.13,8>undecane (123366-49-4) → 1,8-dimethyl-9-phenyl-3,6-diazahomoadamantane-9-ol (1361308-85-1)

Guidance literature:

bromobenzene; With lithium; In diethyl ether;

6,8-dimethyl-7-oxo-diazatricyclo<4.3.1.1^3,8>undecane; In diethyl ether; at 20 ℃; for 5.5h;

DOI:10.1134/S1070428012010198

upstream raw materials:

5,7-Dimethyl-6-oxo-1,3-diazaadamantane

ethylene dibromide

1,3,6,8-tetraazatricyclo[4.4.1.1^3,8]dodecane

pentan-3-one

Downstream raw materials:

1,8-dimethyl-9-phenyl-3,6-diazahomoadamantane-9-ol