2-(4-Aminophenyl)-1-phenylethanone

Base Information

Chemical Name:2-(4-Aminophenyl)-1-phenylethanone
CAS No.:2440-20-2
Molecular Formula:C14H13NO
Molecular Weight:211.26
Hs Code.:2922399090
DSSTox Substance ID:DTXSID20467616
Nikkaji Number:J80.488F
Wikidata:Q82294652
Mol file:2440-20-2.mol

Synonyms:2-(4-Aminophenyl)-1-phenylethanone;2440-20-2;SCHEMBL3060994;DTXSID20467616

Suppliers and Price of 2-(4-Aminophenyl)-1-phenylethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-(4-Aminophenyl)-1-phenylethanone

Chemical Property:

PSA：43.09000
LogP:3.27540
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:211.099714038
Heavy Atom Count:16
Complexity:225

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)CC2=CC=C(C=C2)N

Technology Process of 2-(4-Aminophenyl)-1-phenylethanone

There total 9 articles about 2-(4-Aminophenyl)-1-phenylethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 3769-82-2
2-(4-nitrophenyl)-1-phenylethanone

: 2440-20-2
2-(4-aminophenyl)-1-phenylethan-1-one

Guidance literature:: With acetic acid; zinc; at 20 ℃;
DOI:10.1016/j.bmcl.2011.07.052

Reference yield: 52.0%

: 1197-55-3
4-aminophenylacetic acid

: 71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1
benzene

: 2440-20-2
2-(4-aminophenyl)-1-phenylethan-1-one

Guidance literature:: With PPA; In dichloromethane; at 80 ℃; for 2h;
DOI:10.1080/00397910500522124

Reference yield:

: 98-80-6
phenylboronic acid

: 2440-20-2
2-(4-aminophenyl)-1-phenylethan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 4,4'-bipyridine; trifluoroacetic acid; palladium diacetate / tetrahydrofuran; water / 36 h / 80 °C / Inert atmosphere

2: ammonium chloride; iron / water; ethanol / 4 h / Inert atmosphere; Heating

With 4,4'-bipyridine; palladium diacetate; iron; ammonium chloride; trifluoroacetic acid; In tetrahydrofuran; ethanol; water;
DOI:10.1021/acs.jafc.1c06404