2,3-Dihydroxy-3-methylpentanoic acid

Base Information

• Chemical Name: 2,3-Dihydroxy-3-methylpentanoic acid
• CAS No.: 562-43-6
• Molecular Formula: C6H12 O4
• Molecular Weight: 148.159
• European Community (EC) Number: 852-567-6
• DSSTox Substance ID: DTXSID00971589
• Nikkaji Number: J2.364.785K
• Wikipedia: 2,3-Dihydroxy-3-methylpentanoic_acid
• Wikidata: Q2823199
• Metabolomics Workbench ID: 75578
• Mol file: 562-43-6.mol

Synonyms:2,3-dihydroxy-3-methylpentanoic acid

Chemical Property of 2,3-Dihydroxy-3-methylpentanoic acid

Chemical Property:

• Vapor Pressure: 9.89E-06mmHg at 25°C
• Boiling Point: 333.2°Cat760mmHg
• Flash Point: 169.5°C
• PSA: 77.76000
• Density: 1.259g/cm³
• LogP: -0.40710
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 148.07355886
• Heavy Atom Count: 10
• Complexity: 134

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C)(C(C(=O)O)O)O

Technology Process of 2,3-Dihydroxy-3-methylpentanoic acid

There total 2 articles about 2,3-Dihydroxy-3-methylpentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-glucose (50-99-7) → 2-oxo-3(RS)-methylvaleric acid (1460-34-0) + L-isoleucine (73-32-5,959215-79-3,18875-42-8) + α,β-dihydroxy-β-methylvalerate (562-43-6)

Guidance literature:

With Escherichia coli TDGA; at 37 ℃; for 28h; Title compound not separated from byproducts; Microbiological reaction;

DOI:10.1271/bbb.63.672

Reference yield:

→ α,β-dihydroxy-β-methylvalerate (562-43-6)

Guidance literature:

2,3-Epoxy-3-methyl-valeriansaeure-ethylester: 1) wss. NaOH 2) Rk. prod., sd. W., 4h;

DOI:10.1007/BF00908038

upstream raw materials:

D-glucose