1-Oxo Mirtazapine (Mirtazapine Impurity C)

Base Information

Chemical Name:1-Oxo Mirtazapine (Mirtazapine Impurity C)
CAS No.:191546-96-0
Molecular Formula:C17H17N3O
Molecular Weight:279.341
Hs Code.:2933599550
Mol file:191546-96-0.mol

Synonyms:1-Oxo Mirtazapine (Mirtazapine Impurity C);Mirtazapine Related Compound C (50 mg) (2-Methyl-3,4,10,14b-tetrahydrobenzo[c]pyrazino[1,2-a]pyrido[3,2-f]azepin-1(2H)-one);3,4,10,14b-Tetrahydro-2-Methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepin-1(2H)-one;Mirtazapine IMpurity C;Mirtazapine EP IMpurity C (USP RC C);Mirtazapine EP IMpurity C;Mirtazapine Related CoMpound C

Suppliers and Price of 1-Oxo Mirtazapine (Mirtazapine Impurity C)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-OxoMirtazapine(MirtazapineImpurityC)
5mg
$ 755.00

TRC
1-OxoMirtazapine(MirtazapineImpurityC)
1mg
$ 160.00

Biosynth Carbosynth
1-Oxo mirtazapine
25 mg
$ 3000.00

Biosynth Carbosynth
1-Oxo mirtazapine
10 mg
$ 1635.00

Biosynth Carbosynth
1-Oxo mirtazapine
5 mg
$ 1000.00

Biosynth Carbosynth
1-Oxo mirtazapine
1 mg
$ 280.00

Biosynth Carbosynth
1-Oxo mirtazapine
2 mg
$ 500.00

American Custom Chemicals Corporation
MIRTAZAPINE IMPURITY C 95.00%
5MG
$ 499.82

Total 17 raw suppliers

Chemical Property of 1-Oxo Mirtazapine (Mirtazapine Impurity C)

Chemical Property:

Melting Point:206-209?C
PSA：36.44000
LogP:2.00840
Storage Temp.:Refrigerator
Solubility.:DMSO, Methanol

Purity/Quality:

99% ^*data from raw suppliers

1-OxoMirtazapine(MirtazapineImpurityC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 1-Oxo Mirtazapine (Mirtazapine Impurity C; Mirtazapine USP Related Compound C) is an impurity of Mirtazapine. Mirtazapine EP Impurity C. Mirtazapine Impurity C.

Technology Process of 1-Oxo Mirtazapine (Mirtazapine Impurity C)

There total 5 articles about 1-Oxo Mirtazapine (Mirtazapine Impurity C) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

: 1071504-87-4
N-(2-chloro-ethyl)-N-methyl-2-(10,11-dihydro-5H-benzo[e]pyrido[2,3-b]azepin-10-yl)-carboxamide

: 191546-96-0
3,4,10,14b-tetrahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepin-1(2H)-one

Guidance literature:: With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; for 3h; Heating / reflux;

Reference yield:

: 130277-16-6
2-amino-3-benzylpyridine

: 191546-96-0
3,4,10,14b-tetrahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepin-1(2H)-one

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid / 0.5 h / 20 °C

2: 110.25 h / 20 - 70 °C

3: thionyl chloride / chloroform / 20 °C

4: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 3 h / Heating / reflux

With thionyl chloride; potassium carbonate; potassium iodide; sulfuric acid; In chloroform; N,N-dimethyl-formamide;

Reference yield:

: 1071504-70-5,1071504-71-6
10,11-dihydro-5H-benzo[e]pyrido[2,3-b]azepine-10-carboxylic acid methyl ester

: 191546-96-0
3,4,10,14b-tetrahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepin-1(2H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran / 72.5 h / 20 - 75 °C

2: thionyl chloride / chloroform / 20 °C

3: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 3 h / Heating / reflux

With thionyl chloride; potassium carbonate; potassium iodide; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide;