1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylic acid

Base Information

Chemical Name:1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylic acid
CAS No.:862821-16-7
Molecular Formula:C12H14O4
Molecular Weight:222.241
Hs Code.:2917399590
DSSTox Substance ID:DTXSID40469718
Wikidata:Q82297555
Mol file:862821-16-7.mol

Synonyms:1-(3,4-dimethoxyphenyl)cyclopropanecarboxylic acid;862821-16-7;1-(3,4-dimethoxyphenyl)cyclopropane-1-carboxylic Acid;MFCD08442257;SCHEMBL77742;DTXSID40469718;AC6996;AKOS000124780;AB90502;BS-50650;SY034321;CS-0313403;FT-0751305;1-(3,4-dimethoxyphenyl)cyclopropanecarboxylicacid;A923581;1-(3,4-dimethoxyphenyl)cyclopropane carboxylic acid;Z361883632

Suppliers and Price of 1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(3,4-dimethoxyphenyl)cyclopropanecarboxylicAcid
100mg
$ 60.00

SynQuest Laboratories
1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylic acid
1 g
$ 312.00

Crysdot
1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylicAcid 95+%
5g
$ 832.00

Chemenu
1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylicAcid 95%
5g
$ 785.00

Apolloscientific
1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylicacid
500mg
$ 153.00

Apolloscientific
1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylicacid
1g
$ 283.00

Alichem
1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylicAcid
5g
$ 840.00

AK Scientific
1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylicacid
1g
$ 802.00

Acrotein
1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylicacid 97%
1g
$ 400.40

ACHEMBLOCK
1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylicacid 95%
250MG
$ 215.00

Total 7 raw suppliers

Chemical Property of 1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:376.412°C at 760 mmHg
Flash Point:145.972°C
PSA：55.76000
Density:1.262g/cm³
LogP:1.82000
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:222.08920892
Heavy Atom Count:16
Complexity:272

Purity/Quality:

97% ^*data from raw suppliers

1-(3,4-dimethoxyphenyl)cyclopropanecarboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C2(CC2)C(=O)O)OC

Technology Process of 1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylic acid

There total 2 articles about 1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.5%

: 20802-15-7
1-(3,4-dimethoxyphenyl)cyclopropanecarbonitrile

: 862821-16-7
1-(3,4-dimethoxyphenyl)cyclopropanecarboxylic acid

Guidance literature:: 1-(3,4-dimethoxyphenyl)cyclopropanecarbonitrile; With potassium hydroxide; In ethylene glycol; for 12h; Heating / reflux;

With hydrogenchloride; water; pH=4 - 5;

Reference yield:

: 93-17-4
3,4-dimethoxyphenylacetonitrile

: 862821-16-7
1-(3,4-dimethoxyphenyl)cyclopropanecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: TEBA; aq. KOH / 48 h / 20 °C

2: 0.76 g / KOH; ethylene glycol / Heating

With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; ethylene glycol;
DOI:10.1021/jm050756e

Reference yield: 60.2%

: 862821-16-7
1-(3,4-dimethoxyphenyl)cyclopropanecarboxylic acid

: 5036-48-6
3-(1H-imidazol-1-yl)propan-1-amine

: 862821-17-8
N-(3-(1H-imidazol-1-yl)propyl)-1-(3,4-dimethoxyphenyl)cyclopropanecarboxamide

Guidance literature:: 1-(3,4-dimethoxyphenyl)cyclopropanecarboxylic acid; With 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran; at -5 ℃; for 0.0833333h;

3-(1H-imidazol-1-yl)propan-1-amine; In tetrahydrofuran; at 20 ℃; for 10h;
DOI:10.1021/jm050756e