3-(4-methanesulfonyl-phenyl)-3-oxo-propionic acid ethyl ester

Base Information

Chemical Name:3-(4-methanesulfonyl-phenyl)-3-oxo-propionic acid ethyl ester
CAS No.:53090-47-4
Molecular Formula:C₁₂H₁₄O₅S
Molecular Weight:270.306
Hs Code.:
Mol file:53090-47-4.mol

Synonyms:3-(4-methanesulfonyl-phenyl)-3-oxo-propionic acid ethyl ester

Suppliers and Price of 3-(4-methanesulfonyl-phenyl)-3-oxo-propionic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of 3-(4-methanesulfonyl-phenyl)-3-oxo-propionic acid ethyl ester

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

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Technology Process of 3-(4-methanesulfonyl-phenyl)-3-oxo-propionic acid ethyl ester

There total 3 articles about 3-(4-methanesulfonyl-phenyl)-3-oxo-propionic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 64-17-5
ethanol

: 1404448-94-7
2,2-dimethyl-5-(4-(methylsulfonyl)benzoyl)-1,3-dioxane-4,6-dione

: 53090-47-4
3-(4-methanesulfonyl-phenyl)-3-oxo-propionic acid ethyl ester

Guidance literature:: Reflux;

Reference yield:

: 40913-92-6
4-methylsulfonylbenzoyl chloride

: 1007476-32-5
sodium ethyl acetylacetate enolate

: 22821-70-1
methyl 4-(methanesulfonyl)benzoate

: 53090-47-4
3-(4-methanesulfonyl-phenyl)-3-oxo-propionic acid ethyl ester

Guidance literature:: With benzene; Behandeln des Reaktionsprodukts mit methanol. Natriummethylat;
DOI:10.1039/jr9480001506

Reference yield:

: 4052-30-6
4-methylsulfonylbenzoic acid

: 53090-47-4
3-(4-methanesulfonyl-phenyl)-3-oxo-propionic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

2: Reflux

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane;