Methyl 2-[acetyl(methyl)amino]-3-O,4-O,6-O-trimethyl-2-deoxy-α-D-glucopyranoside

Base Information

• Chemical Name: Methyl 2-[acetyl(methyl)amino]-3-O,4-O,6-O-trimethyl-2-deoxy-α-D-glucopyranoside
• CAS No.: 36757-11-6
• Molecular Formula: C13H25NO6
• Molecular Weight: 291.3407
• Mol file: 36757-11-6.mol

Synonyms:Methyl 2-[acetyl(methyl)amino]-3-O,4-O,6-O-trimethyl-2-deoxy-α-D-glucopyranoside

Chemical Property of Methyl 2-[acetyl(methyl)amino]-3-O,4-O,6-O-trimethyl-2-deoxy-α-D-glucopyranoside

Chemical Property:

• PSA: 66.46000
• LogP: -0.11900

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl 2-[acetyl(methyl)amino]-3-O,4-O,6-O-trimethyl-2-deoxy-α-D-glucopyranoside

There total 3 articles about Methyl 2-[acetyl(methyl)amino]-3-O,4-O,6-O-trimethyl-2-deoxy-α-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

methyl 2-acetamido-3,4,6-tri-O-methyl-2-deoxy-α-D-glucopyranoside (7380-60-1) + methyl iodide (74-88-4) → methyl 2-(acetylmethylamino)-2-deoxy-3,4,6-tri-O-methyl-α-D-glucopyranoside (36757-11-6)

Guidance literature:

With dimethyl sulfoxide; deprotonated form; In dimethyl sulfoxide; for 48h;

DOI:10.1002/hlca.19960790127

Reference yield:

methyl 2-acetylamido-2-deoxy-D-glucoside (6082-04-8) → methyl 2-(acetylmethylamino)-2-deoxy-3,4,6-tri-O-methyl-α-D-glucopyranoside (36757-11-6)

Guidance literature:

With ammonia; sodium; methyl iodide;

DOI:10.1038/1841718a0

Reference yield:

Methyl 2-acetamido-2-deoxy-3,4,6-tri-O-methyl-α,β-D-glucopyranoside (96744-17-1) → methyl 2--2-deoxy-3,4,6-tri-O-methyl-β-D-glucopyranoside (6195-87-5) + methyl 2-(acetylmethylamino)-2-deoxy-3,4,6-tri-O-methyl-α-D-glucopyranoside (36757-11-6)

Guidance literature:

Yield given. Yields of byproduct given; methylation;

DOI:10.1016/0008-6215(86)85064-9

upstream raw materials:

methyl 2-acetylamido-2-deoxy-D-glucoside

Methyl 2-acetamido-2-deoxy-3,4,6-tri-O-methyl-α,β-D-glucopyranoside

methyl 2-acetamido-3,4,6-tri-O-methyl-2-deoxy-α-D-glucopyranoside

methyl iodide