Fluoromethane

Base Information

• Chemical Name: Fluoromethane
• CAS No.: 593-53-3
• Deprecated CAS: 102801-15-0,1519044-65-5
• Molecular Formula: CH3 F
• Molecular Weight: 34.0332
• Hs Code.: 2903430010
• European Community (EC) Number: 209-796-6
• UN Number: 2454
• UNII: 54A9X6F0CM
• DSSTox Substance ID: DTXSID6060474,DTXSID101315196
• Nikkaji Number: J1.245.458I,J298.853D,J2.696D
• Wikipedia: Fluoromethane,Carbon_monofluoride,Fluoromethylidyne
• Wikidata: Q421738,Q82939051
• Metabolomics Workbench ID: 51861
• ChEMBL ID: CHEMBL116838
• Mol file: 593-53-3.mol

Synonyms:fluoromethane;fluoromethane ion (1+);fluoromethane, 13C-labeled;fluoromethane, 14C-labeled;fluoromethane, 18F-labeled;methyl fluoride

Chemical Property of Fluoromethane

Chemical Property:

• Appearance/Colour: colourless gas with an ether-like odour
• Vapor Pressure: 21100mmHg at 25°C
• Melting Point: -115°C
• Refractive Index: 1.1740
• Boiling Point: -79°C
• Flash Point: °C
• PSA: 0.00000
• Density: 0,877 g/cm³
• LogP: 0.58570
• Water Solubility.: 1.787g/L(29.9 oC)
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 34.021878258
• Heavy Atom Count: 2
• Complexity: 2
• Transport DOT Label: Flammable Gas

Purity/Quality:

99% min ^*data from raw suppliers

Fluoromethane 99% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,F+
• Statements: 12
• Safety Statements: 16-33

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Solvents -> Chlorofluorocarbons
• Canonical SMILES: CF

Technology Process of Fluoromethane

There total 123 articles about Fluoromethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

dimethyl sulfate (77-78-1) → Methyl fluoride (593-53-3)

Guidance literature:

With potassium fluoride; In water; at 100 ℃; for 5h; Solvent; Reagent/catalyst; Temperature;

Reference yield: 99.0%

1,1,1,3,3-pentafluoro-3-methoxy-2-trifluoromethylpropane (382-26-3) → Methyl fluoride (593-53-3) + 3,3,3-trifluoro-2-trifluoromethyl-propionyl fluoride (382-22-9)

Guidance literature:

With titanium(IV) oxide; at 150 ℃; Reagent/catalyst; Temperature; Gas phase; Flow reactor;

Reference yield: 90.8%

(Z)-4,4,5,5,5-Pentafluoro-3-methoxy-2-trifluoromethyl-pent-2-enoyl fluoride (84047-25-6) → Methyl fluoride (593-53-3) + pentafluoropropionyl(trifluoromethyl)ketene (53352-88-8)

Guidance literature:

titanium(IV) fluoride; In neat (no solvent); Heating;

DOI:10.1021/jo00195a025

upstream raw materials:

methanol

1,2-difluoroethane

phenylsulfonyl fluoride

methylene chloride

Downstream raw materials:

2,3-dimethylfuran

2,4-dimethylfuran

2,5-dimethylfuran

2,3-dimethyl-1H-pyrrole

Refernces

• 1、 Pritchard,Thommarson. "". . p. 1674. Retrieved 1967.
• 2、 Kato, Shuji,Hacaloglu, Jale,Davico, Gustavo E.,DePuy, Charles H.,Bierbaum, Veronica M.. "Deuterium kinetic isotope effects in the gas-phase SN2 reactions of solvated fluoride ions with methyl halides". . p. 9887 - 9891. Retrieved 2004.
• 3、 Davis, Larry ,P.,Burggraf, Larry, W.,Gordon, Mark, S.,Baldridge, Kim, K.. "A Theoretical Study of Fluorine Atom and Fluoride Ion Attack on Methane and Silane". . p. 4415 - 4419. Retrieved 1985.
• 4、 Lacher et al.. "-". . p. 1454. Retrieved 1956.
• 5、 Snegirev, V. F.,Galakhov, M. V.,Petrov, V. A.,Makarov, K. N.,Bakhmutov, V. I.. "POLYFLUORINATED ANIONS AND CATIONS - INTERMEDIATES IN REACTIONS OF FLUORINE-CONTAINING VINYL ETHERS". . p. 1194 - 1200. Retrieved 1986.
• 6、 Moore,Smith,Stewart. "Rates of processes initiated by pulsed laser production of F atoms in the presence of HCl, CH4, and CF3H". . p. 813 - 825. Retrieved 1994.
• 7、 Su, Timothy,Morris, Robert A.,Viggiano, A. A.,Paulson, John F.. "Kinetic Energy and Temperature Dependences for the Reaction of F(1-) with Halogenated Methanes: Experiment and Theory". . p. 8426 - 8430. Retrieved 1990.
• 8、 Misochko, E. Ya.,Benderskii, V. A.,Goldschleger, A. U.. "Photolysis of Fluorine Molecules Trapped in Solid Methane at 15 K: Evidence of the Reaction of Vibrationally Excited CH3F Molecules with F2". . p. 13917 - 13920. Retrieved 1995.
• 9、 -. "COMPOSITION INCLUDING FLUOROMETHANE AND METHOD FOR PRODUCING SAME". Paragraph 0068-0070. . Retrieved 2018/06/04.
• 10、 -. "Method for preparing fluorinated compound CH2F-R (R is H or CF3) through difluoromethane pyrolysis". Paragraph 0046-0049. . Retrieved 2017/05/18.