methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate

Base Information

Chemical Name:methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate
CAS No.:1268619-58-4
Molecular Formula:C12H18BNO4
Molecular Weight:251.09
Hs Code.:
Mol file:1268619-58-4.mol

Synonyms:methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate

Suppliers and Price of methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4-(Methoxycarbonyl)-1h-Pyrrol-2-Yl)BoronicAcidPinacolEster
5mg
$ 65.00

TRC
(4-(Methoxycarbonyl)-1h-Pyrrol-2-Yl)BoronicAcidPinacolEster
2.5mg
$ 45.00

Crysdot
Methyl5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate 95+%
5g
$ 2679.00

Crysdot
Methyl5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate 95+%
1g
$ 892.00

Chemenu
Methyl5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate 95%
1g
$ 843.00

AK Scientific
Methyl5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-pyrrole-3-carboxylate
2.5g
$ 1679.00

Total 6 raw suppliers

Chemical Property of methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate

Chemical Property:

PSA：60.55000
LogP:1.10050

Purity/Quality:

97% ^*data from raw suppliers

(4-(Methoxycarbonyl)-1h-Pyrrol-2-Yl)BoronicAcidPinacolEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate

There total 2 articles about methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 2703-17-5
methyl 1H-pyrrole-3-carboxylate

: 73183-34-3
bis(pinacol)diborane

: 1268619-58-4
methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate

Guidance literature:: With 4,4'-di-tert-butyl-2,2'-bipyridine; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; In cyclohexane; at 90 ℃; for 5h;

Reference yield:

: 2703-17-5
methyl 1H-pyrrole-3-carboxylate

: 73183-34-3
bis(pinacol)diborane

: 1268619-58-4
methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate

: C₁₂H₁₈BNO₄

: C₁₈H₂₉B₂NO₆

Guidance literature:: bis(pinacol)diborane; With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine; In tetrahydrofuran; Inert atmosphere; Glovebox;

methyl 1H-pyrrole-3-carboxylate; In tetrahydrofuran; at 100 ℃; for 20h; regioselective reaction; Sealed tube; Inert atmosphere;
DOI:10.1002/anie.201916015

Reference yield: 77.0%

: 1268619-58-4
methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-3-carboxylate

: 1268619-82-4
3-(2-chloropyridin-4-yloxy)-4-fluoro-N-(2-fluoro-5-methylphenyl)benzamide

: 1268619-83-5
methyl 5-[4-(2-fluoro-5-{[(2-fluoro-5-methylphenyl)amino]carbonyl}phenoxy)pyridin-2-yl]-1H-pyrrole-3-carboxylate

Guidance literature:: With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water; at 100 ℃; for 15h; Sealed vessel; Inert atmosphere;