(2S,4S)-1-(benzyloxycarbonyl)pyrrolidine-2,4-dicarboxylic acid

Base Information

• Chemical Name: (2S,4S)-1-(benzyloxycarbonyl)pyrrolidine-2,4-dicarboxylic acid
• CAS No.: 130830-73-8
• Molecular Formula: C14H15NO6
• Molecular Weight: 293.272
• Mol file: 130830-73-8.mol

Synonyms:(2S,4S)-1-(benzyloxycarbonyl)pyrrolidine-2,4-dicarboxylic acid

Chemical Property of (2S,4S)-1-(benzyloxycarbonyl)pyrrolidine-2,4-dicarboxylic acid

Chemical Property:

• PSA: 104.14000
• LogP: 1.12080

Purity/Quality:

≥95% ^*data from raw suppliers

(2S,4S)-1-(Benzyloxycarbonyl)pyrrolidine-2,4-dicarboxylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (2S,4S)-1-(Benzyloxycarbonyl)pyrrolidine-2,4-dicarboxylic Acid can be used as transport inhibitors.

Technology Process of (2S,4S)-1-(benzyloxycarbonyl)pyrrolidine-2,4-dicarboxylic acid

There total 7 articles about (2S,4S)-1-(benzyloxycarbonyl)pyrrolidine-2,4-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

N-(benzyloxycarbonyl)-cis-4-carboxy-L-proline dimethyl ester (130830-69-2) → N-(benzyloxycarbonyl)-cis-4-carboxy-L-proline (130830-73-8)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water; for 0.833333h;

DOI:10.1021/jm00106a037

Reference yield:

(2S,4R)-ethyl N1-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate (103667-57-8) → N-(benzyloxycarbonyl)-cis-4-carboxy-L-proline (130830-73-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 98 percent / pyridine / CHCl₃ / 72 h / Ambient temperature

2: 66 percent / dimethylsulfoxide / 4 h / 80 °C

3: 94 percent / HCl / 84 h / Ambient temperature

4: 97 percent / 4 M NaOH / tetrahydrofuran; H₂O / 0.83 h

With pyridine; hydrogenchloride; sodium hydroxide; In tetrahydrofuran; chloroform; water; dimethyl sulfoxide;

DOI:10.1021/jm00106a037

Reference yield:

N-(benzyloxycarbonyl)-cis-4-cyano-L-proline ethyl ester (130830-65-8) → N-(benzyloxycarbonyl)-cis-4-carboxy-L-proline (130830-73-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / HCl / 84 h / Ambient temperature

2: 97 percent / 4 M NaOH / tetrahydrofuran; H₂O / 0.83 h

With hydrogenchloride; sodium hydroxide; In tetrahydrofuran; water;

DOI:10.1021/jm00106a037

upstream raw materials:

N-(benzyloxycarbonyl)-cis-4-carboxy-L-proline dimethyl ester

(2S,4R)-ethyl N¹-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate

N-(benzyloxycarbonyl)-cis-4-cyano-L-proline ethyl ester

1-benzyl 2-ethyl(2S,4R)-4-[[(4-methylbenzene)sulfonyl]oxy]pyrrolidine-1,2-dicarboxylate

Downstream raw materials:

cis-4-carboxy-L-proline

cis-4-Carboxy-L-proline

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 130830-73-8 (2S,4S)-1-(benzyloxycarbonyl)pyrrolidine-2,4-dicarboxylic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send