103667-57-8

Basic information

• Product Name: 1-CBZ-4(R)-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID ETHYL ESTER
• Synonyms: 1-CBZ-4(R)-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID ETHYL ESTER;1-Cbz-4-Hydroxy-L-Proline Ethyl Ester;(4R)-1-Benzyl 2-ethyl 4-hydroxypyrrolidine-1,2-dicarboxylate;1-Cbz-trans-4-Hydroxy-L-proline ethyl ester
• CAS NO: 103667-57-8
• Molecular Formula: C₁₅H₁₉NO₅
• Molecular Weight: 293.31506
• Mol File: 103667-57-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 434.1±45.0 °C(Predicted)
• Appearance: /
• Density: 1.279±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 14.28±0.40(Predicted)
• CAS DataBase Reference: 1-CBZ-4(R)-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CBZ-4(R)-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID ETHYL ESTER(103667-57-8)
• EPA Substance Registry System: 1-CBZ-4(R)-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID ETHYL ESTER(103667-57-8)

Safety Data

• Hazardous Substances Data: 103667-57-8(Hazardous Substances Data)

Usage

General Description

1-CBZ-4(R)-Hydroxypyrrolidine-2-carboxylic acid ethyl ester is a chemical compound with the molecular formula C14H19NO4. It is an ethyl ester derivative of 1-CBZ-4(R)-Hydroxypyrrolidine-2-carboxylic acid, which is a key intermediate in the synthesis of pharmaceuticals and other bioactive compounds. 1-CBZ-4(R)-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID ETHYL ESTER is commonly used as a chiral building block in the synthesis of various pharmaceutical drugs, including antivirals, antifungals, and anti-infective agents. It is also used as a precursor in the production of peptide-based drugs. The compound is important in the pharmaceutical industry due to its ability to introduce chirality into molecules and its role in the synthesis of biologically active compounds.

Upstream product

• 501-53-1 benzyl chloroformate 
• 61478-25-9 (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid ethyl ester 
• 33996-30-4 trans-4-hydroxy-L-proline ethyl ester hydrochloride 
• 1063998-64-0 (2S,4R)-4-Hydroxy-pyrrolidine-2-carbonyl chloride 
• 75-03-6 ethyl iodide 
• 13504-85-3 (2S,4R)-1-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid 
• 64-17-5 ethanol 
• 51-35-4 4R-4-hydroxyproline 

Downstream Products

• 64927-38-4 cis-4-carboxy-L-proline 
• 130830-73-8 N-(benzyloxycarbonyl)-cis-4-carboxy-L-proline 
• 130830-65-8 N-(benzyloxycarbonyl)-cis-4-cyano-L-proline ethyl ester 
• 130830-69-2 N-(benzyloxycarbonyl)-cis-4-carboxy-L-proline dimethyl ester 
• 130830-79-4 Mosher amide of cis-4-carboxy-L-proline dimethyl ester 
• 586396-26-1 cis-N-(benzyloxycarbonyl)-4-carboxy-L-proline methyl ester 
• 1430105-81-9 C₁₅H₁₉NO₅ 
• 1446655-22-6 C₂₁H₂₃NO₄ 
• 1446655-24-8 C₂₈H₂₉NO₄ 
• 1446653-56-0 (2S,4S)-4-(benzyloxymethyl)-1-(2,2-diphenylacetyl)pyrrolidine-2-carboxylic acid 
• 1446655-26-0 C₂₃H₂₄N₂O₆ 
• 1446655-28-2 C₂₃H₂₂N₂O₅ 
• 1446655-30-6 C₁₅H₁₆N₂O₃ 
• 1446655-32-8 C₂₉H₂₆N₂O₄ 

Relevant articles and documents

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