D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, 2,3,4,6-tetrakis(2,2-dimethylpropanoate), (1S)-

Base Information

Chemical Name:D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, 2,3,4,6-tetrakis(2,2-dimethylpropanoate), (1S)-
CAS No.:1283129-18-9
Molecular Formula:C44H57FO9S
Molecular Weight:780.996
Hs Code.:
European Community (EC) Number:695-878-0
DSSTox Substance ID:DTXSID501021038
Mol file:1283129-18-9.mol

Synonyms:1283129-18-9;D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, 2,3,4,6-tetrakis(2,2-dimethylpropanoate), (1S)-;[(2R,3R,4R,5S,6S)-3,4,5-tris(2,2-dimethylpropanoyloxy)-6-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methylphenyl]oxan-2-yl]methyl 2,2-dimethylpropanoate;SCHEMBL1585154;DTXSID501021038

Suppliers and Price of D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, 2,3,4,6-tetrakis(2,2-dimethylpropanoate), (1S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 33 raw suppliers

Chemical Property of D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, 2,3,4,6-tetrakis(2,2-dimethylpropanoate), (1S)-

Chemical Property:

Vapor Pressure:0-0Pa at 20-25℃
PSA：142.67000
Density:1.19g/cm3 at 20℃
LogP:9.35630
XLogP3:10.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:17
Exact Mass:780.37073273
Heavy Atom Count:55
Complexity:1330

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=C(C=C1)C2C(C(C(C(O2)COC(=O)C(C)(C)C)OC(=O)C(C)(C)C)OC(=O)C(C)(C)C)OC(=O)C(C)(C)C)CC3=CC=C(S3)C4=CC=C(C=C4)F
Isomeric SMILES:CC1=C(C=C(C=C1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)COC(=O)C(C)(C)C)OC(=O)C(C)(C)C)OC(=O)C(C)(C)C)OC(=O)C(C)(C)C)CC3=CC=C(S3)C4=CC=C(C=C4)F
Use Description {(1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol 2,3,4,6-tetrakis(2,2-dimethylpropanoate)}, a specific chemical compound, serves distinct roles across various fields. In the pharmaceutical sector, it plays a crucial role as a potential pharmaceutical compound or intermediate, contributing to drug discovery and the development of molecules with potential therapeutic applications. In organic synthesis, (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol 2,3,4,6-tetrakis(2,2-dimethylpropanoate) can serve as a valuable building block, enabling the creation of complex molecular structures for research purposes. Moreover, in the field of medicinal chemistry, it may be explored for its potential interactions with biological systems and its role in designing novel drug candidates. Its applications in pharmaceuticals, organic synthesis, and medicinal chemistry underscore its significance in driving innovation, scientific exploration, and potential medical advancements within these different domains.

Technology Process of D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, 2,3,4,6-tetrakis(2,2-dimethylpropanoate), (1S)-

There total 6 articles about D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, 2,3,4,6-tetrakis(2,2-dimethylpropanoate), (1S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.6%

: 898566-17-1
(2-(4-fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene)

: 81058-27-7
2,3,4,6-tetra-O-pivaloyl-α-D-glucopyranosyl bromide

: 1283129-18-9
(2S,3S,4R,5R,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(pivaloyloxymethyl)tetrahydro-2H-pyran-3,4,5-triyl tris(2,2-dimethylpropanoate)

Guidance literature:: (2-(4-fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene); With n-butyllithium; zinc dibromide; In n-heptane; dibutyl ether; toluene; at -10 - 25 ℃; for 2.5h; Inert atmosphere;

2,3,4,6-tetra-O-pivaloyl-α-D-glucopyranosyl bromide; In n-heptane; dibutyl ether; toluene; at 95 ℃; for 6.5h; Product distribution / selectivity;

Reference yield:

C₁₈H₁₄FLiS: C₁₈H₁₄FLiS

: 958300-05-5
2,3,4,6-tetra-O-pivaloyl-β-D-glucopyranosylbromide

: 1283129-18-9
(2S,3S,4R,5R,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(pivaloyloxymethyl)tetrahydro-2H-pyran-3,4,5-triyl tris(2,2-dimethylpropanoate)

Guidance literature:: C₁₈H₁₄FLiS; With lithium bromide; zinc dibromide; In cyclopropyl methyl ether; at -25 - 0 ℃;

2,3,4,6-tetra-O-pivaloyl-β-D-glucopyranosylbromide; In cyclopropyl methyl ether; toluene; at 20 - 65 ℃; for 48.5h;

Reference yield:

: 958300-05-5
2,3,4,6-tetra-O-pivaloyl-β-D-glucopyranosylbromide

: 1283129-24-7
C₃₆H₂₈F₂S₂Zn

: 1283129-18-9
(2S,3S,4R,5R,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(pivaloyloxymethyl)tetrahydro-2H-pyran-3,4,5-triyl tris(2,2-dimethylpropanoate)

Guidance literature:: 2,3,4,6-tetra-O-pivaloyl-β-D-glucopyranosylbromide; C₃₆H₂₈F₂S₂Zn; In ethyl acetate; toluene; at 75 ℃; for 21h; Inert atmosphere;

With ammonium chloride; In water; toluene; Product distribution / selectivity;