Benzyl tert-butyl (2-methylpropane-1,2-diyl)dicarbamate

Base Information

• Chemical Name: Benzyl tert-butyl (2-methylpropane-1,2-diyl)dicarbamate
• CAS No.: 169954-67-0
• Molecular Formula: C₁₇H₂₆N₂O₄
• Molecular Weight: 322.404
• Mol file: 169954-67-0.mol

Synonyms:Benzyl tert-butyl (2-methylpropane-1,2-diyl)dicarbamate;N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methylpropyl]Carbamic acid phenylmethyl ester

Chemical Property of Benzyl tert-butyl (2-methylpropane-1,2-diyl)dicarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzyl tert-butyl (2-methylpropane-1,2-diyl)dicarbamate

There total 6 articles about Benzyl tert-butyl (2-methylpropane-1,2-diyl)dicarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

di-tert-butyl dicarbonate (24424-99-5) + (2-amino-2-methylpropyl)carbamic acid benzyl ester (156892-82-9) → (2-benzyloxycarbonylamino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester (169954-67-0)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1039/c3cc40961a

Reference yield:

(2-amino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester (320581-09-7) + benzyl chloroformate (501-53-1,94274-21-2) → (2-benzyloxycarbonylamino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester (169954-67-0)

Guidance literature:

With triethylamine; In acetonitrile; at 0 - 20 ℃; for 1h;

Reference yield:

N-(Benzyloxycarbonyloxy)succinimide (13139-17-8) + (2-amino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester (320581-09-7) → (2-benzyloxycarbonylamino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester (169954-67-0)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 1h;

upstream raw materials:

di-tert-butyl dicarbonate

(2-amino-2-methylpropyl)carbamic acid benzyl ester

benzyl phenyl carbonate

(2-amino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester

Downstream raw materials:

(2-amino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester

C₁₉H₃₀N₂O₄

(2-amino-2-methylpropyl)carbamic acid benzyl ester