4-BROMO-3,5-DIMETHOXYBENZOYL HYDRAZINE

Base Information

• Chemical Name: 4-BROMO-3,5-DIMETHOXYBENZOYL HYDRAZINE
• CAS No.: 263567-38-0
• Molecular Formula: C₉H₁₁BrN₂O₃
• Molecular Weight: 275.102
• Hs Code.: 2928000090
• Mol file: 263567-38-0.mol

Synonyms:4-BROMO-3,5-DIMETHOXYBENZOYL HYDRAZINE;4-bromo-3,5-dimethoxyBenzoic acid hydrazide

Chemical Property of 4-BROMO-3,5-DIMETHOXYBENZOYL HYDRAZINE

Chemical Property:

• PKA: 11.22±0.10(Predicted)
• PSA: 77.07000
• Density: 1.518±0.06 g/cm3(Predicted)
• LogP: 2.34490
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

4-Bromo-3,5-dimethoxybenzohydrazide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BROMO-3,5-DIMETHOXYBENZOYL HYDRAZINE

There total 2 articles about 4-BROMO-3,5-DIMETHOXYBENZOYL HYDRAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

methyl 4-bromo-3,5-dimethoxybenzoate (26050-64-6) → C9H11BrN2O3 (263567-38-0)

Guidance literature:

With hydrazine hydrate; In ethanol; at 50 ℃; for 8h;

DOI:10.1039/c5ra21326f

Reference yield:

4-bromo-3,5-dimethoxybenzoic acid (56518-42-4) → C9H11BrN2O3 (263567-38-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid / 16 h / Reflux

2: hydrazine hydrate / ethanol / 8 h / 50 °C

With sulfuric acid; hydrazine hydrate; In ethanol;

DOI:10.1039/c5ra21326f

Reference yield:

C9H11BrN2O3 (263567-38-0) + 1-Naphthyl isocyanate (86-84-0) → 2-(3,5-dimethoxybenzoyl)-N-(naphthalen-1-yl)hydrazine-1-carboxamide (444932-31-4) + C20H18(2)HN3O4

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran; methanol / 1 h

2: palladium on activated charcoal; deuterium / N,N-dimethyl-formamide / 30.5 h / 20 °C

With palladium on activated charcoal; deuterium; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;

DOI:10.1039/c5ra21326f

upstream raw materials:

4-bromo-3,5-dimethoxybenzoic acid

methyl 4-bromo-3,5-dimethoxybenzoate

Downstream raw materials:

2-(3,5-dimethoxybenzoyl)-N-(naphthalen-1-yl)hydrazine-1-carboxamide