2-nitro-4-bromo-5-fluoroanisole

Base Information

• Chemical Name: 2-nitro-4-bromo-5-fluoroanisole
• CAS No.: 1352244-77-9
• Molecular Formula: C7H5BrFNO3
• Molecular Weight: 250.024
• Mol file: 1352244-77-9.mol

Synonyms:2-nitro-4-bromo-5-fluoroanisole;1-bromo-2-fluoro-4-methoxy-5-nitrobenzene

Chemical Property of 2-nitro-4-bromo-5-fluoroanisole

Chemical Property:

• Boiling Point: 290.5±35.0 °C(Predicted)
• PSA: 55.05000
• Density: 1.716±0.06 g/cm3(Predicted)
• LogP: 3.02820
• Storage Temp.: 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

1-Bromo-2-fluoro-4-methoxy-5-nitrobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-nitro-4-bromo-5-fluoroanisole

There total 4 articles about 2-nitro-4-bromo-5-fluoroanisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1-bromo-2-fluoro-4-methoxybenzene (458-50-4) → 1-bromo-2-fluoro-4-methoxy-5-nitro-benzene (1352244-77-9)

Guidance literature:

With sulfuric acid; potassium nitrate; at 0 ℃; for 0.5h;

Reference yield: 86.0%

5-bromo-2,4-difluoronitrobenzene (345-24-4) + sodium methylate (124-41-4) → 1-bromo-4-fluoro-2-methoxy-5-nitrobenzene (935288-20-3) + 1-bromo-2-fluoro-4-methoxy-5-nitro-benzene (1352244-77-9)

Guidance literature:

In methanol; at 0 - 20 ℃; for 22h;

Reference yield:

4-bromo-5-fluoro-2-nitrophenol (1016234-87-9) + methyl iodide (74-88-4) → 1-bromo-2-fluoro-4-methoxy-5-nitro-benzene (1352244-77-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 45 ℃; for 0.75h;

upstream raw materials:

5-bromo-2,4-difluoronitrobenzene

sodium methylate

1-bromo-2-fluoro-4-methoxybenzene

4-bromo-5-fluoro-2-nitrophenol

Downstream raw materials:

4-bromo-5-fluoro-7-methoxy-3,3-dimethyl-1-(2-nitrophenyl)indoline

5-bromo-4-fluoro-2-methoxyaniline

(5-bromo-4-fluoro-2-methoxyphenyl)hydrazine

1-{2-[5-fluoro-4-(4-fluorophenyl)-7-hydroxy-3,3-dimethyl-2,3-dihydro-1H-indol-1-yl]phenyl}-3-[4-(trifluoromethoxy)phenyl]urea

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1352244-77-9 2-nitro-4-bromo-5-fluoroanisole

Send

Send

Metric Ton KG G Pound L ML

Send

Send