2-Chloro-4-(trifluoromethyl)benzyl bromide

Base Information

• Chemical Name: 2-Chloro-4-(trifluoromethyl)benzyl bromide
• CAS No.: 279252-26-5
• Molecular Formula: C8H5BrClF3
• Molecular Weight: 273.48
• Hs Code.: 2903999090
• Mol file: 279252-26-5.mol

Synonyms:2-Chloro-4-(trifluoromethyl)benzyl bromide;1-(bromomethyl)-2-chloro-4-(trifluoromethyl)benzene;BENZENE, 1-(BROMOMETHYL)-2-CHLORO-4-(TRIFLUOROMETHYL)-

Chemical Property of 2-Chloro-4-(trifluoromethyl)benzyl bromide

Chemical Property:

• PSA: 0.00000
• LogP: 4.25370

Purity/Quality:

98%+ ^*data from raw suppliers

2-Chloro-4-(trifluoromethyl)benzyl bromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Chloro-4-(trifluoromethyl)benzyl bromide

There total 4 articles about 2-Chloro-4-(trifluoromethyl)benzyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(2-chloro-4-(trifluoromethyl)phenyl)methanol (56456-51-0) → 1-(bromomethyl)-2-chloro-4-(trifluoromethyl)benzene (279252-26-5)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; In tetrahydrofuran; at 0 - 30 ℃; for 2h;

Reference yield: 99.0%

(2-chloro-4-(trifluoromethyl)phenyl)methanol (56456-51-0) + carbon tetrabromide (558-13-4) → 1-(bromomethyl)-2-chloro-4-(trifluoromethyl)benzene (279252-26-5)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; diethyl ether; hexane;

Reference yield:

4-methoxy-2,4-dimethylvaleronitrile + 2-Chloro-4-(trifluoromethyl)toluene (74483-47-9) → 1-(bromomethyl)-2-chloro-4-(trifluoromethyl)benzene (279252-26-5)

Guidance literature:

With N-Bromosuccinimide; sodium hydrogencarbonate; In tetrachloromethane; hexane; ethyl acetate;

upstream raw materials:

(2-chloro-4-(trifluoromethyl)phenyl)methanol

2-Chloro-4-(trifluoromethyl)toluene

4-bromomethyl-3-chloroiodobenzene

carbon tetrabromide

Downstream raw materials:

ethyl 3-{1-[2-chloro-4-(trifluoromethyl)benzyl]-3-isopropoxy-1H-pyrazol-5-yl}propanoate

3-(2-Chloro-4-trifluoromethylbenzyl)-2,7-dimethyl-3H-imidazo[4,5-b]pyridine-5-carboxylic acid

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