2-(2-Amino-3-benzoyl-5-chlorophenyl)acetamide

Base Information

Chemical Name:2-(2-Amino-3-benzoyl-5-chlorophenyl)acetamide
CAS No.:78281-71-7
Molecular Formula:C₁₅H₁₃ClN₂O₂
Molecular Weight:288.733
Hs Code.:
European Community (EC) Number:940-022-6,809-720-7
Mol file:78281-71-7.mol

Synonyms:78281-71-7;2-Amino-3-benzoyl-5-chlorobenzeneacetamide;2-(2-amino-3-benzoyl-5-chlorophenyl)acetamide;2-Amino-3-benzoyl-5-chlorophenylacetamide;starbld0004550;SCHEMBL7531015;BNUTYMOAQFOMEB-UHFFFAOYSA-N;DB-346696

Suppliers and Price of 2-(2-Amino-3-benzoyl-5-chlorophenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Amino-3-benzoyl-5-chlorobenzeneacetamide
1g
$ 1320.00

TRC
2-Amino-3-benzoyl-5-chlorobenzeneacetamide
100mg
$ 165.00

Total 8 raw suppliers

Chemical Property of 2-(2-Amino-3-benzoyl-5-chlorophenyl)acetamide

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:288.0665554
Heavy Atom Count:20
Complexity:369

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-3-benzoyl-5-chlorobenzeneacetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C2=CC(=CC(=C2N)CC(=O)N)Cl
Uses 2-Amino-3-benzoyl-5-chlorobenzeneacetamide is an impurity in the synthesis of Nepafenac enac.

Technology Process of 2-(2-Amino-3-benzoyl-5-chlorophenyl)acetamide

There total 4 articles about 2-(2-Amino-3-benzoyl-5-chlorophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 78281-60-4
2-amino-3-benzoyl-5-chloro-α-(methylthio)phenylacetamide

: 78281-71-7
2-amino-3-benzoyl-5-chlorophenylacetamide

Guidance literature:: In N-methyl-acetamide; ethanol;

Reference yield:

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 78281-71-7
2-amino-3-benzoyl-5-chlorophenylacetamide

Guidance literature:: Multi-step reaction with 3 steps

1: tert-butylhypochlorite / dichloromethane / 0.17 h / 20 - 35 °C

2: N-chlorophthalimide / dichloromethane / 3.5 h / -20 - -5 °C

3: Raney-Ni

With N-chlorophthalimide; tert-butylhypochlorite; In dichloromethane;
DOI:10.2174/157017812802139582

Reference yield:

: 719-59-5
5-chloro-2-aminobenzophenone

: 78281-71-7
2-amino-3-benzoyl-5-chlorophenylacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: N-chlorophthalimide / dichloromethane / 3.5 h / -20 - -5 °C

2: Raney-Ni

With N-chlorophthalimide; In dichloromethane;
DOI:10.2174/157017812802139582