1-(3-amino-4,5,6-trimethyl-thieno[2,3-b]pyridin-2-yl)ethanone

Base Information

• Chemical Name: 1-(3-amino-4,5,6-trimethyl-thieno[2,3-b]pyridin-2-yl)ethanone
• CAS No.: 915920-34-2
• Molecular Formula: C₁₂H₁₄N₂OS
• Molecular Weight: 234.322
• Mol file: 915920-34-2.mol

Synonyms:CHEMBRDG-BB 5603272;1-(3-AMINO-4,5,6-TRIMETHYLTHIENO[2,3-B]PYRIDIN-2-YL)ETHANONE;1-(3-amino-4,5,6-trimethylthieno[2,3-b]pyridin-2-yl)ethanone(SALTDATA: FREE)

Chemical Property of 1-(3-amino-4,5,6-trimethyl-thieno[2,3-b]pyridin-2-yl)ethanone

Chemical Property:

• Vapor Pressure: 2.59E-07mmHg at 25°C
• Boiling Point: 421.5°C at 760 mmHg
• Flash Point: 208.7°C
• Density: 1.24g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(3-amino-4,5,6-trimethyl-thieno[2,3-b]pyridin-2-yl)ethanone

There total 1 articles about 1-(3-amino-4,5,6-trimethyl-thieno[2,3-b]pyridin-2-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

4-(but-2-en-2-yl)morpholine (13809-02-4) + Cyanothioacetamide (7357-70-2) + acetaldehyde (75-07-0,9002-91-9) + 1-bromoacetone (598-31-2) → 1-(3-amino-2-acetyl-4,5,6-trimethylthieno[2,3-b]-pyridin-2-yl)ethanone (915920-34-2)

Guidance literature:

Cyanothioacetamide; acetaldehyde; With triethylamine; In ethanol; at 20 ℃; for 0.5h;

4-(but-2-en-2-yl)morpholine; In ethanol; for 26h;

1-bromoacetone; With potassium hydroxide; In ethanol; water; for 3h;

DOI:10.1134/S107042801511010X

upstream raw materials:

4-(but-2-en-2-yl)morpholine

Cyanothioacetamide

acetaldehyde

1-bromoacetone