(2RS,3RS)-3-(2-ETHOXYPHENOXY)-2-HYDROXY-1-(4-NITROBENZOYLOXY)-3-PHENYLPROPANE

Base Information

Chemical Name:(2RS,3RS)-3-(2-ETHOXYPHENOXY)-2-HYDROXY-1-(4-NITROBENZOYLOXY)-3-PHENYLPROPANE
CAS No.:98769-70-1
Molecular Formula:C₂₄H₂₃NO₇
Molecular Weight:437.449
Hs Code.:
Mol file:98769-70-1.mol

Synonyms:(2RS,3RS)-3-(2-ETHOXYPHENOXY)-2-HYDROXY-1-(4-NITROBENZOYLOXY)-3-PHENYLPROPANE;(2R,3S)-rel-

Suppliers and Price of (2RS,3RS)-3-(2-ETHOXYPHENOXY)-2-HYDROXY-1-(4-NITROBENZOYLOXY)-3-PHENYLPROPANE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2RS,3RS)-3-(2-Ethoxyphenoxy)-2-hydroxy-1-(4-nitrobenzoyloxy)-3-phenylpropane
25mg
$ 120.00

TRC
(2RS,3RS)-3-(2-Ethoxyphenoxy)-2-hydroxy-1-(4-nitrobenzoyloxy)-3-phenylpropane
10mg
$ 85.00

TRC
(2RS,3RS)-3-(2-Ethoxyphenoxy)-2-hydroxy-1-(4-nitrobenzoyloxy)-3-phenylpropane
250mg
$ 970.00

Medical Isotopes, Inc.
(2RS,3RS)-3-(2-Ethoxyphenoxy)-2-hydroxy-1-(4-nitrobenzoyloxy)-3-phenylpropane
125 mg
$ 1640.00

American Custom Chemicals Corporation
(2RS,3RS)-3-(2-ETHOXYPHENOXY)-2-HYDROXY-1-(4-NITROBENZOYLOXY)-3-PHENYLPROPANE 95.00%
250MG
$ 1593.90

American Custom Chemicals Corporation
(2RS,3RS)-3-(2-ETHOXYPHENOXY)-2-HYDROXY-1-(4-NITROBENZOYLOXY)-3-PHENYLPROPANE 95.00%
25MG
$ 704.55

Total 6 raw suppliers

Chemical Property of (2RS,3RS)-3-(2-ETHOXYPHENOXY)-2-HYDROXY-1-(4-NITROBENZOYLOXY)-3-PHENYLPROPANE

Chemical Property:

Melting Point:94-95°C
PSA：110.81000
LogP:4.85470
Solubility.:Dichloromethane, Ethyl Acetate

Purity/Quality:

97% ^*data from raw suppliers

(2RS,3RS)-3-(2-Ethoxyphenoxy)-2-hydroxy-1-(4-nitrobenzoyloxy)-3-phenylpropane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses An intermediate in the synthesis of Reboxetine (R142000).0

Technology Process of (2RS,3RS)-3-(2-ETHOXYPHENOXY)-2-HYDROXY-1-(4-NITROBENZOYLOXY)-3-PHENYLPROPANE

There total 4 articles about (2RS,3RS)-3-(2-ETHOXYPHENOXY)-2-HYDROXY-1-(4-NITROBENZOYLOXY)-3-PHENYLPROPANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 122-04-3
4-nitro-benzoyl chloride

: 98769-69-8,98819-70-6,127781-32-2
(2RS,3SR)-3-(2-ethoxyphenoxy)-1,2-dihydroxy-3-phenylpropane

: 98769-70-1,98819-71-7
(2RS,3SR)-3-(2-ethoxyphenoxy)-2-hydroxy-1-(4-nitrobenzoyloxy)-3-phenylpropane

Guidance literature:: In pyridine; at -10 ℃; for 2h;
DOI:10.1016/S0040-4020(01)96541-X

Reference yield:

: 4407-36-7
(2E)-3-phenyl-2-propen-1-ol

: 98769-70-1,98819-71-7
(2RS,3SR)-3-(2-ethoxyphenoxy)-2-hydroxy-1-(4-nitrobenzoyloxy)-3-phenylpropane

Guidance literature:: Multi-step reaction with 3 steps

1: MCPBA / CH₂Cl₂ / 0 deg C, 1.5 h, then RT, 24 h

2: 1.) NaOH / 1.) H₂O, 70 deg C; 2.) H₂O, 70 deg C, 2.5 h

3: 61 percent / pyridine / 2 h / -10 °C

With sodium hydroxide; 3-chloro-benzenecarboperoxoic acid; In pyridine; dichloromethane;
DOI:10.1016/S0040-4020(01)96541-X

Reference yield:

: 94-71-3
2-Ethoxyphenol

: 98769-70-1,98819-71-7
(2RS,3SR)-3-(2-ethoxyphenoxy)-2-hydroxy-1-(4-nitrobenzoyloxy)-3-phenylpropane

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaOH / 1.) H₂O, 70 deg C; 2.) H₂O, 70 deg C, 2.5 h

2: 61 percent / pyridine / 2 h / -10 °C

With sodium hydroxide; In pyridine;
DOI:10.1016/S0040-4020(01)96541-X