1-(Benzyloxycarbonyl)-3-(N-tert-butoxycarbonylamino)-3-methylpyrrolidine

Base Information

Chemical Name:1-(Benzyloxycarbonyl)-3-(N-tert-butoxycarbonylamino)-3-methylpyrrolidine
CAS No.:927389-50-2
Molecular Formula:C18H26N2O4
Molecular Weight:334
Hs Code.:
Mol file:927389-50-2.mol

Synonyms:1-(Benzyloxycarbonyl)-3-(N-tert-butoxycarbonylamino)-3-methylpyrrolidine

Suppliers and Price of 1-(Benzyloxycarbonyl)-3-(N-tert-butoxycarbonylamino)-3-methylpyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Benzyl3-((tert-butoxycarbonyl)amino)-3-methylpyrrolidine-1-carboxylate 95+%
1g
$ 772.00

Chemenu
benzyl3-((tert-butoxycarbonyl)amino)-3-methylpyrrolidine-1-carboxylate 95%
1g
$ 729.00

American Custom Chemicals Corporation
BENZYL-3-((TERT-BUTOXYCARBONYL)AMINO)-3-METHYLPYRROLIDINE-1-CARBOXYLATE 95.00%
5MG
$ 503.32

Alichem
Benzyl3-((tert-butoxycarbonyl)amino)-3-methylpyrrolidine-1-carboxylate
1g
$ 628.00

Total 6 raw suppliers

Chemical Property of 1-(Benzyloxycarbonyl)-3-(N-tert-butoxycarbonylamino)-3-methylpyrrolidine

Chemical Property:

PSA：71.36000
LogP:3.45460
Storage Temp.:2-8°C

Purity/Quality:

95+% ^*data from raw suppliers

Benzyl3-((tert-butoxycarbonyl)amino)-3-methylpyrrolidine-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(Benzyloxycarbonyl)-3-(N-tert-butoxycarbonylamino)-3-methylpyrrolidine

There total 3 articles about 1-(Benzyloxycarbonyl)-3-(N-tert-butoxycarbonylamino)-3-methylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 912444-75-8,1412254-20-6
1-((benzyloxy)carbonyl)-3-methylpyrrolidine-3-carboxylic acid

: 75-65-0
tert-butyl alcohol

: 927389-50-2
1-benzyloxycarbonyl-3-(N-tert-butoxycarbonylamino)-3-methylpyrrolidine

Guidance literature:: 1-((benzyloxy)carbonyl)-3-methylpyrrolidine-3-carboxylic acid; tert-butyl alcohol; With diphenyl phosphoryl azide; triethylamine; for 1h; Heating; Reflux;

for 24h; sealed tube; Heating;

Reference yield:

: 912444-74-7
1-benzyl 3-methyl 3-methylpyrrolidine-1,3-dicarboxylate

: 927389-50-2
1-benzyloxycarbonyl-3-(N-tert-butoxycarbonylamino)-3-methylpyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: water; lithium hydroxide / ethanol / 1 h / Heating

1.2: pH 3 - 4

2.1: diphenyl phosphoryl azide; triethylamine / 1 h / Heating; Reflux

2.2: 24 h / sealed tube; Heating

With diphenyl phosphoryl azide; water; triethylamine; lithium hydroxide; In ethanol;

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 927389-50-2
1-benzyloxycarbonyl-3-(N-tert-butoxycarbonylamino)-3-methylpyrrolidine

Guidance literature:: Multi-step reaction with 4 steps

1.1: potassium carbonate / tetrahydrofuran; water / 2 h / 0 - 20 °C

2.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.33 h / -78 °C

2.2: -78 - 20 °C

3.1: water; lithium hydroxide / ethanol / 1 h / Heating

3.2: pH 3 - 4

4.1: diphenyl phosphoryl azide; triethylamine / 1 h / Heating; Reflux

4.2: 24 h / sealed tube; Heating

With diphenyl phosphoryl azide; water; potassium carbonate; triethylamine; lithium hydroxide; lithium hexamethyldisilazane; In tetrahydrofuran; ethanol; water;