(R)-N-(2-(4-aMinophenyl)propyl)propane-2-sulfonaMide 4-Methylbenzenesulfonate

Base Information

• Chemical Name: (R)-N-(2-(4-aMinophenyl)propyl)propane-2-sulfonaMide 4-Methylbenzenesulfonate
• CAS No.: 376594-64-8
• Molecular Formula: C12H20N2O2S
• Molecular Weight: 256.369
• Mol file: 376594-64-8.mol

Synonyms:(R)-N-(2-(4-aMinophenyl)propyl)propane-2-sulfonaMide 4-Methylbenzenesulfonate

Chemical Property of (R)-N-(2-(4-aMinophenyl)propyl)propane-2-sulfonaMide 4-Methylbenzenesulfonate

Chemical Property:

• PSA: 80.57000
• LogP: 3.75300

Purity/Quality:

99% ^*data from raw suppliers

(R)-N-(2-(4-Aminophenyl)propyl)propane-2-sulfonamide 4-methylbenzenesulfonate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-N-(2-(4-aMinophenyl)propyl)propane-2-sulfonaMide 4-Methylbenzenesulfonate

There total 13 articles about (R)-N-(2-(4-aMinophenyl)propyl)propane-2-sulfonaMide 4-Methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

R-2-(4-nitrophenyl)-1-(2-propanesulfonamido)-propane (376594-72-8) → R-2-(4-aminophenyl)-1-(2-propanesulfonamido)-propane (376594-64-8)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃; for 6h; under 2844.39 Torr;

Reference yield: 88.1%

[(2R)-2-(4-aminophenyl)propyl][(methylethyl)sulfonyl]amine p-toluenesulfonate (376594-65-9) → R-2-(4-aminophenyl)-1-(2-propanesulfonamido)-propane (376594-64-8)

Guidance literature:

With sodium hydrogencarbonate; In dichloromethane; water; pH=6.5;

Reference yield:

[(2R)-2-(3-nitrophenyl)propyl][(methylethyl)sulfonyl]amine (1449337-13-6) + [(2R)-2-(2-nitrophenyl)propyl][(methylethyl)sulfonyl]amine + R-2-(4-nitrophenyl)-1-(2-propanesulfonamido)-propane (376594-72-8) → R-2-(4-aminophenyl)-1-(2-propanesulfonamido)-propane (376594-64-8)

Guidance literature:

With hydrogen; 5% palladium-on-charcoal; In tetrahydrofuran; ethanol; at 20 - 25 ℃; for 16 - 20h;

upstream raw materials:

R-2-(4-nitrophenyl)-1-(2-propanesulfonamido)-propane

2-(4-nitrophenyl)propanoic acid

4-nitrobenzeneacetic acid

4-nitrophenylacetyl fluoride

Downstream raw materials:

[(2R)-2-(4-aminophenyl)propyl][(methylethyl)sulfonyl]amine p-toluenesulfonate