376594-72-8

Upstream product

• 10147-37-2 Isopropylsulfonyl chloride 
• 376594-71-7 R-2-(4-nitrophenyl)-1-propylamine 
• 375345-97-4 propane-2-sulfonic acid (2-phenylpropyl)amide 
• 158044-99-6 (2R)-2-(4-nitrophenyl)propylamine 
• 400629-37-0 ((2S)-2-phenylpropyl)[(methylethyl)sulfonyl]amine 
• 869304-73-4 4R-benzyl-3-(2R-(4-nitrophenyl)propionyl)-2-oxazolidinone 
• 869304-72-3 4R-benzyl-3-(4-nitrophenylacetyl)-2-oxazolidinone 
• 376594-70-6 N-(R-2-(4-nitrophenyl)-1-propyl)phthalimide 
• 869304-77-8 R-2-(4-nitropheny)-1-propyl azide 
• 185130-37-4 R-2-(4-nitrophenyl)-1-propanol 
• 78507-53-6 4-nitrophenylacetyl fluoride 
• 104-03-0 4-nitrobenzeneacetic acid 
• 19910-33-9 2-(4-nitrophenyl)propanoic acid 

Downstream Products

• 376594-67-1 LY 450108 
• 376594-64-8 R-2-(4-aminophenyl)-1-(2-propanesulfonamido)-propane 

Relevant academic research and scientific papers

Synthesis of 14C-labeled and tritiated AMPA potentiator LY450108

Asymmetric synthesis of AMPA potentiator LY450108-[14C] containing 14C-label attached to the chiral center of the molecule, was accomplished based on Evans' chiral oxazolidinone auxiliary method. Diastereoselective methylation of p-n

Sulfonamide derivatives

The present invention relates to a compound of formula (Ia) or a pharmaceutically acceptable salt thereof which is useful for the treatment of conditions associated with glutamate hypofunction, such as psychiatric and neurological disorders. 1

Heterocyclic sulfonamide derivatives

The present invention provides certain heterocyclic sulfonamide derivatives of formula (I): useful for potentiating glutamate receptor function in a patient and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders.