3-chloro-N-(4-methoxyphenyl)pyridin-2-amine

Base Information

Chemical Name:3-chloro-N-(4-methoxyphenyl)pyridin-2-amine
CAS No.:370571-31-6
Molecular Formula:C12H11ClN2O
Molecular Weight:234.685
Hs Code.:
Mol file:370571-31-6.mol

Synonyms:3-chloro-N-(4-methoxyphenyl)pyridin-2-amine;2-AMino-N-(4-Methoxyphenyl)pyridine, 97%

Suppliers and Price of 3-chloro-N-(4-methoxyphenyl)pyridin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of 3-chloro-N-(4-methoxyphenyl)pyridin-2-amine

Chemical Property:

PSA：34.15000
LogP:3.56020

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-chloro-N-(4-methoxyphenyl)pyridin-2-amine

There total 2 articles about 3-chloro-N-(4-methoxyphenyl)pyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 2402-77-9
2,3-dichloro-pyridine

: 104-94-9
4-methoxy-aniline

: 370571-31-6
3-chloro-N-(4-methoxyphenyl)pyridin-2-amine

Guidance literature:: With potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate; In toluene; for 18h; Heating;
DOI:10.1016/S0040-4020(01)00659-7

Reference yield: 38.0%

: 2402-77-9
2,3-dichloro-pyridine

: 104-94-9
4-methoxy-aniline

: 78750-82-0
6-methoxy-9H-pyrido[2,3-b]indole

: 370571-31-6
3-chloro-N-(4-methoxyphenyl)pyridin-2-amine

Guidance literature:: 2,3-dichloro-pyridine; 4-methoxy-aniline; With palladium diacetate; triphenylphosphine; sodium t-butanolate; In o-xylene; at 120 ℃; for 3h; Inert atmosphere;

With palladium diacetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; tricyclohexylphosphine tetrafluoroborate; In N,N-dimethyl acetamide; o-xylene; at 145 ℃; for 16h; Inert atmosphere;
DOI:10.1021/jo802776m

Reference yield: 99.0%

: 370571-31-6
3-chloro-N-(4-methoxyphenyl)pyridin-2-amine

: 98-80-6
phenylboronic acid

: 1294517-62-6
N-(4-methoxyphenyl)-3-phenylpyridin-2-amine

Guidance literature:: With palladium diacetate; potassium carbonate; XPhos; In toluene; at 150 ℃; for 14h; Inert atmosphere;
DOI:10.1002/ejoc.201001583