(6-2-[3-(4-Phenylcarbamoyl-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-D5-pyrrol-1-yl]-ethyl-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester

Base Information

Chemical Name:(6-2-[3-(4-Phenylcarbamoyl-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-D5-pyrrol-1-yl]-ethyl-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester
CAS No.:265989-34-2
Molecular Formula:C₄₀H₄₇FN₂O₅
Molecular Weight:659.782
Hs Code.:
Mol file:265989-34-2.mol

Synonyms:(6-2-[3-(4-Phenylcarbamoyl-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-D5-pyrrol-1-yl]-ethyl-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester;(4R,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-Methylethyl)-3-phenyl-4-[(phenyl-d5-aMino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester

Suppliers and Price of (6-2-[3-(4-Phenylcarbamoyl-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-D5-pyrrol-1-yl]-ethyl-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(6-{2-[3-(4-Phenylcarbamoyl)-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-d5-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-aceticAcid,tert-ButylEster
25mg
$ 1320.00

Medical Isotopes, Inc.
(6-2-[3-(4-Phenylcarbamoyl-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-d5-pyrrol-1-yl]-ethyl-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester
5 mg
$ 1995.00

Medical Isotopes, Inc.
(6-2-[3-(4-Phenylcarbamoyl-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-d5-pyrrol-1-yl]-ethyl-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester
1 mg
$ 750.00

American Custom Chemicals Corporation
(6-[2-[3-(4-PHENYLCARBAMOYL)-5-(4-FLUORO-PHENYL)-2-ISOPROPYL-4-PHENYL-D5-PYRROL-1-YL]-ETHYL]-2,2-DIMETHYL-[1,3]-DIOXANE-4-YL)ACETIC ACID-TERT-BUTYL ESTER 95.00%
5MG
$ 505.48

Total 2 raw suppliers

Chemical Property of (6-2-[3-(4-Phenylcarbamoyl-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-D5-pyrrol-1-yl]-ethyl-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester

Chemical Property:

PSA：82.28000
LogP:9.75300

Purity/Quality:

97% ^*data from raw suppliers

(6-{2-[3-(4-Phenylcarbamoyl)-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-d5-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-aceticAcid,tert-ButylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (6-2-[3-(4-Phenylcarbamoyl-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-D5-pyrrol-1-yl]-ethyl-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester

There total 5 articles about (6-2-[3-(4-Phenylcarbamoyl-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-D5-pyrrol-1-yl]-ethyl-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4165-61-1
aniline-d5

: 265989-34-2
C₄₀H₄₂⁽²⁾H₅FN₂O₅

Guidance literature:: Multi-step reaction with 4 steps

1: 97 percent / toluene / 4 h / 80 °C

2: 15.26 g / β-alanine; glacial acetic acid / hexane / 25 h / Heating

3: 4.7 g / 3-ethyl-5-(2-hydroxyethyl)-4-methylthiazolium bromide; triethylamine / ethanol / 21 h / 75 - 80 °C

4: 4.07 g / pivalic acid / tetrahydrofuran; toluene; heptane / 24 h / Heating

With 3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; acetic acid; triethylamine; 3-amino propanoic acid; Trimethylacetic acid; In tetrahydrofuran; ethanol; hexane; n-heptane; toluene; 1: Acylation / 2: Condensation / 3: Addition / 4: Cycloaddition;
DOI:10.1002/(SICI)1099-1344(20000315)43:3<261::AID-JLCR312>3.0.CO;2-T

Reference yield:

: isobutyryl Meldrum's acid

: 265989-34-2
C₄₀H₄₂⁽²⁾H₅FN₂O₅

Guidance literature:: Multi-step reaction with 4 steps

1: 97 percent / toluene / 4 h / 80 °C

2: 15.26 g / β-alanine; glacial acetic acid / hexane / 25 h / Heating

3: 4.7 g / 3-ethyl-5-(2-hydroxyethyl)-4-methylthiazolium bromide; triethylamine / ethanol / 21 h / 75 - 80 °C

4: 4.07 g / pivalic acid / tetrahydrofuran; toluene; heptane / 24 h / Heating

With 3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; acetic acid; triethylamine; 3-amino propanoic acid; Trimethylacetic acid; In tetrahydrofuran; ethanol; hexane; n-heptane; toluene; 1: Acylation / 2: Condensation / 3: Addition / 4: Cycloaddition;
DOI:10.1002/(SICI)1099-1344(20000315)43:3<261::AID-JLCR312>3.0.CO;2-T

Reference yield:

: 265989-29-5
N-d5-phenyl isobutyrylacetamide

: 265989-34-2
C₄₀H₄₂⁽²⁾H₅FN₂O₅

Guidance literature:: Multi-step reaction with 3 steps

1: 15.26 g / β-alanine; glacial acetic acid / hexane / 25 h / Heating

2: 4.7 g / 3-ethyl-5-(2-hydroxyethyl)-4-methylthiazolium bromide; triethylamine / ethanol / 21 h / 75 - 80 °C

3: 4.07 g / pivalic acid / tetrahydrofuran; toluene; heptane / 24 h / Heating

With 3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; acetic acid; triethylamine; 3-amino propanoic acid; Trimethylacetic acid; In tetrahydrofuran; ethanol; hexane; n-heptane; toluene; 1: Condensation / 2: Addition / 3: Cycloaddition;
DOI:10.1002/(SICI)1099-1344(20000315)43:3<261::AID-JLCR312>3.0.CO;2-T