2-acetaMido-4-chloro-5-Methylbenzoic acid

Base Information

Chemical Name:2-acetaMido-4-chloro-5-Methylbenzoic acid
CAS No.:1204312-39-9
Molecular Formula:C10H10ClNO3
Molecular Weight:227.647
Hs Code.:
Mol file:1204312-39-9.mol

Synonyms:2-acetaMido-4-chloro-5-Methylbenzoic acid;2-(acetylamino)-4-chloro-5-methylbenzoic acid

Suppliers and Price of 2-acetaMido-4-chloro-5-Methylbenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-acetamido-4-chloro-5-methylbenzoicacid
10mg
$ 60.00

ChemScene
2-acetamido-4-chloro-5-methylbenzoicacid
500mg
$ 495.00

Total 6 raw suppliers

Chemical Property of 2-acetaMido-4-chloro-5-Methylbenzoic acid

Chemical Property:

Boiling Point:432.9±45.0 °C(Predicted)
PKA:3.33±0.10(Predicted)
PSA：69.89000
Density:1.394±0.06 g/cm3(Predicted)
LogP:2.95450

Purity/Quality:

98%min ^*data from raw suppliers

2-acetamido-4-chloro-5-methylbenzoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-acetaMido-4-chloro-5-Methylbenzoic acid

There total 4 articles about 2-acetaMido-4-chloro-5-Methylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 201230-82-2
carbon monoxide

: 7149-79-3
N-(3-chloro-4-methylphenyl)acetamide

: 1204312-39-9
4-chloro-5-methyl-N-acetylanthranilic acid

Guidance literature:: With Pd(OTf)2(MeCN)4; water; toluene-4-sulfonic acid; p-benzoquinone; In 1,4-dioxane; at 20 - 80 ℃; under 760.051 Torr;
DOI:10.1021/ja9077705

Reference yield: 37.0%

: 124-38-9,18923-20-1
carbon dioxide

: 116010-06-1
N-(2-bromo-5-chloro-4-methylphenyl)acetamide

: 1204312-39-9
4-chloro-5-methyl-N-acetylanthranilic acid

Guidance literature:: N-(2-bromo-5-chloro-4-methylphenyl)acetamide; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

carbon dioxide; In tetrahydrofuran; hexane; at 20 ℃; for 0.25h; Inert atmosphere;

Reference yield:

: 95-74-9,827571-80-2
3-chloro-p-toluidine

: 1204312-39-9
4-chloro-5-methyl-N-acetylanthranilic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyridine / ethyl acetate / 2 h / 0 - 20 °C

2.1: acetic acid; bromine / 20 h / 0 - 20 °C

3.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere

3.2: 0.25 h / 20 °C / Inert atmosphere

With pyridine; n-butyllithium; bromine; acetic acid; In tetrahydrofuran; hexane; ethyl acetate;