5'-Bromospiro[[1,3]dioxane-2,3'-indolin]-2'-one

Base Information

Chemical Name:5'-Bromospiro[[1,3]dioxane-2,3'-indolin]-2'-one
CAS No.:332073-48-0
Molecular Formula:C₁₁H₁₀BrNO₃
Molecular Weight:284.109
Hs Code.:2934999090
DSSTox Substance ID:DTXSID10351853
Nikkaji Number:J2.545.344A
Wikidata:Q82128636
Mol file:332073-48-0.mol

Synonyms:332073-48-0;5'-Bromospiro[[1,3]dioxane-2,3'-indolin]-2'-one;5-Bromo-3,3-(propylenedioxo)-1,3-dihydro-indole-2-one;5'-bromospiro[1,3-dioxane-2,3'-1H-indole]-2'-one;5'-bromospiro[1,3-dioxane-2,3'-indol]-2'(1'H)-one;5-bromospiro[indoline-3,2'-[1,3]dioxan]-2-one;5//'-Bromospiro[[1,3]dioxane-2,3//'-indolin]-2//'-one;BAS 00915168;Oprea1_333501;Oprea1_495548;F3294-0103;SCHEMBL5338177;DTXSID10351853;YWHABBBYNDXUIC-UHFFFAOYSA-N;STK246390;AKOS000582948;CCG-249128;SB65022;CS-0323522;FT-0644448;VU0609187-1;AT-057/40723466;5'-bromo-1',2'-dihydrospiro([1,3]dioxane-2,3'-indole)-2'-one

Suppliers and Price of 5'-Bromospiro[[1,3]dioxane-2,3'-indolin]-2'-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5'-Bromospiro[[1,3]dioxane-2,3'-indolin]-2'-one 95+%
1g
$ 535.00

Chemenu
5-bromospiro[indoline-3,2''-[1,3]dioxan]-2-one 95%
1g
$ 505.00

American Custom Chemicals Corporation
5-BROMO-3,3-(PROPYLENEDIOXO)-1,3-DIHYDRO-INDOLE-2-ONE 95.00%
20G
$ 3234.00

American Custom Chemicals Corporation
5-BROMO-3,3-(PROPYLENEDIOXO)-1,3-DIHYDRO-INDOLE-2-ONE 95.00%
5G
$ 2789.33

American Custom Chemicals Corporation
5-BROMO-3,3-(PROPYLENEDIOXO)-1,3-DIHYDRO-INDOLE-2-ONE 95.00%
1G
$ 1697.85

Alichem
5'-Bromospiro[[1,3]dioxane-2,3'-indolin]-2'-one
1g
$ 475.24

AHH
5-Bromo-3,3-(propylenedioxo)-1,3-dihydro-indole-2-one 95%
0.25g
$ 430.00

Total 6 raw suppliers

Chemical Property of 5'-Bromospiro[[1,3]dioxane-2,3'-indolin]-2'-one

Chemical Property:

PSA：47.56000
LogP:2.12890
Storage Temp.:2-8°C
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:282.98441
Heavy Atom Count:16
Complexity:304

Purity/Quality:

99% ^*data from raw suppliers

5'-Bromospiro[[1,3]dioxane-2,3'-indolin]-2'-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2(C3=C(C=CC(=C3)Br)NC2=O)OC1

Technology Process of 5'-Bromospiro[[1,3]dioxane-2,3'-indolin]-2'-one

There total 4 articles about 5'-Bromospiro[[1,3]dioxane-2,3'-indolin]-2'-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 87-48-9
5-Bromo-1H-indole-2,3-dione

: 504-63-2
trimethyleneglycol

: 332073-48-0
5'-bromospiro[1,3-dioxane-2,3'-indol]-2'(1'H)-one

Guidance literature:: With toluene-4-sulfonic acid; In benzene; for 14h; Reflux;
DOI:10.1016/j.bmc.2009.09.036

Reference yield:

: 106-40-1
4-bromo-aniline

: 332073-48-0
5'-bromospiro[1,3-dioxane-2,3'-indol]-2'(1'H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: sodium sulfate; hydrogenchloride; hydroxylamine hydrochloride / water / 2 h / 85 °C

2: sulfuric acid / 0.5 h / 60 - 90 °C

3: toluene-4-sulfonic acid / toluene / 5 h / 130 °C

With hydrogenchloride; sulfuric acid; hydroxylamine hydrochloride; toluene-4-sulfonic acid; sodium sulfate; In water; toluene;
DOI:10.1016/j.bmc.2012.06.024

Reference yield:

: 66475-83-0
N-(4-bromophenyl)-2-(hydroxyimino) acetamide

: 332073-48-0
5'-bromospiro[1,3-dioxane-2,3'-indol]-2'(1'H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / 0.5 h / 60 - 90 °C

2: toluene-4-sulfonic acid / toluene / 5 h / 130 °C

With sulfuric acid; toluene-4-sulfonic acid; In toluene;
DOI:10.1016/j.bmc.2012.06.024