2-Aminooctadecanoic acid

Base Information

• Chemical Name: 2-Aminooctadecanoic acid
• CAS No.: 5782-80-9
• Molecular Formula: C18H37NO2
• Molecular Weight: 299.497
• Mol file: 5782-80-9.mol

Synonyms:2-Aminooctadecanoic acid

Chemical Property of 2-Aminooctadecanoic acid

Chemical Property:

• Melting Point: 218-220 °C
• Boiling Point: 420.7±28.0 °C(Predicted)
• PKA: 2.54±0.24(Predicted)
• PSA: 63.32000
• Density: 0.923±0.06 g/cm3(Predicted)
• LogP: 5.97000

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Aminooctadecanoic acid

There total 14 articles about 2-Aminooctadecanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

2-aminooctadecanonitrile → 2-amino-octadecanoic acid (5782-80-9)

Guidance literature:

With hydrogenchloride; at 40 ℃; for 6h;

DOI:10.1016/j.tet.2017.03.023

Reference yield:

diethyl ether (60-29-7,927820-24-4) + ethanol (64-17-5) + 6,7-dinitro-octadecanoic acid → 2-amino-octadecanoic acid (5782-80-9) + 2-hydroxystearic acid (629-22-1,26531-80-6) + 6,7-diamino-octadecanoic acid

Guidance literature:

Reference yield:

sodium cyanide (773837-37-9) + n-heptadecanal (629-90-3) → 2-amino-octadecanoic acid (5782-80-9)

Guidance literature:

sodium cyanide; n-heptadecanal; With ammonium chloride; In 1,2-dimethoxyethane; water; at 50 ℃; for 20h; Autoclave;

With hydrogenchloride; at 40 ℃; for 6h;

DOI:10.1016/j.tet.2017.03.023

upstream raw materials:

2-bromostearic acid

ammonia

diethyl ether

ethanol

Downstream raw materials:

2-phthalimido-octadecanoic acid