4-(BroMoMethyl)-2,6-pyridinedicarboxylic Acid 2,6-DiMethyl Ester

Base Information

• Chemical Name: 4-(BroMoMethyl)-2,6-pyridinedicarboxylic Acid 2,6-DiMethyl Ester
• CAS No.: 1040401-17-9
• Molecular Formula: C₁₀H₁₀BrNO₄
• Molecular Weight: 288.098
• Mol file: 1040401-17-9.mol

Synonyms:4-(BroMoMethyl)-2,6-pyridinedicarboxylic Acid 2,6-DiMethyl Ester

Chemical Property of 4-(BroMoMethyl)-2,6-pyridinedicarboxylic Acid 2,6-DiMethyl Ester

Chemical Property:

• PSA: 65.49000
• LogP: 1.54970
• Storage Temp.: Refrigerator
• Solubility.: Dichloromethane

Purity/Quality:

97% ^*data from raw suppliers

4-(Bromomethyl)-2,6-pyridinedicarboxylicAcid2,6-DimethylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-(BroMoMethyl)-2,6-pyridinedicarboxylic Acid 2,6-DiMethyl Ester is used in the preparation of a lanthanide tag designed for site-specific labeling of proteins.

Technology Process of 4-(BroMoMethyl)-2,6-pyridinedicarboxylic Acid 2,6-DiMethyl Ester

There total 1 articles about 4-(BroMoMethyl)-2,6-pyridinedicarboxylic Acid 2,6-DiMethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl 4-tosyloxymethylpyridine-2,6-dicarboxylate (909247-46-7) → 2,6-dimethoxycarbonyl-4-bromomethylpyridine (1040401-17-9)

Guidance literature:

With lithium bromide; In acetone; at 20 ℃; for 2h;

DOI:10.1021/ja803741f

Reference yield: 99.0%

2,6-dimethoxycarbonyl-4-bromomethylpyridine (1040401-17-9) → 4-(mercaptomethyl)pyridine-2,6-dicarboxylic acid (1040401-18-0)

Guidance literature:

2,6-dimethoxycarbonyl-4-bromomethylpyridine; With thiourea; In methanol; Reflux; Inert atmosphere;

With sodium hydroxide; In water; Inert atmosphere; Reflux;

DOI:10.1021/ja803741f

upstream raw materials:

dimethyl 4-tosyloxymethylpyridine-2,6-dicarboxylate

Downstream raw materials:

4-(mercaptomethyl)pyridine-2,6-dicarboxylic acid