trans-Ethyl 4-aminocyclohexanecarboxylate hydrochloride

Base Information

• Chemical Name: trans-Ethyl 4-aminocyclohexanecarboxylate hydrochloride
• CAS No.: 2084-28-8
• Molecular Formula: C₉H₁₇NO₂*ClH
• Molecular Weight: 207.7
• Hs Code.: 2922499990
• European Community (EC) Number: 606-651-2
• NSC Number: 25535
• Mol file: 2084-28-8.mol

Synonyms:2084-28-8;trans-Ethyl 4-aminocyclohexanecarboxylate hydrochloride;61367-17-7;90950-09-7;cis-Ethyl 4-aminocyclohexanecarboxylate hydrochloride;Ethyl 4-aminocyclohexanecarboxylate hydrochloride;cis-4-amino-cyclohexanecarboxylic acid ethyl ester hydrochloride;Ethyl 4-aminocyclohexane-1-carboxylate Hydrochloride;4-Amino-cyclohexanecarboxylic acid ethyl ester hydrochloride;Ethyl trans-4-Aminocyclohexanecarboxylate Hydrochloride;ethyl 4-aminocyclohexane-1-carboxylate;hydrochloride;ethyl cis-4-aminocyclohexanecarboxylate hydrochloride;(trans-4-Carboethoxycyclohexyl)amine Hydrochloride;Ethyl 4-aminocyclohexanecarboxylate HCl;MFCD14635812;Ethyl trans-4-aminocyclohexanecarboxylate HCl;Cyclohexanecarboxylic acid, 4-amino-, ethyl ester, hydrochloride (1:1), trans-;Ethyl cis-4-aminocyclohexanecarboxylate HCl;Cyclohexanecarboxylic acid, 4-amino-, ethyl ester, hydrochloride, cis-;Ethyl trans-4-Amino-cyclohexanecarboxylate HCl;SCHEMBL385320;SCHEMBL853961;SCHEMBL3195558;Ethyl trans-4-amino cyclohexane carboxylate hydrochloride;UPVSMFHQPMRMLP-KMMPGQJCSA-N;UPVSMFHQPMRMLP-KVZVIFLMSA-N;UPVSMFHQPMRMLP-UHFFFAOYSA-N;AMY37760;BCP24225;CAA08428;NSC25535;AB9199;AM9642;MFCD12913688;MFCD22691262;NSC-25535;AKOS016006664;AKOS017343938;AKOS022178491;DS-7960;DS-9419;SB37934;SB39815;AS-44952;SY038011;CS-0043124;CS-0043141;CS-0239163;FT-0668141;C75876;EN300-206920;N10627;EN300-1721192;A868723;A879395;CIS-ETHYL 4-AMINOCYCLOHEXANECARBOXYLATE HCL;cis-ethyl-4-aminocyclohexanecarboxylate hydrochloride;ethyl (1r,4r)-4-aminocyclohexane-1-carboxylate hcl;J-013670;TRANS ETHYL 4-AMINOCYCLOHEXANECARBOXYLATE HCL;trans-Ethyl4-aminocyclohexanecarboxylatehydrochloride;4-amino-cyclohexanecarboxylic acid ethyl ester HCl salt;Z3236099504;(1r,4r)-ethyl 4-aminocyclohexanecarboxylate hydrochloride;trans ethyl 4-aminocyclohexane-1-carboxylate hydrochloride;cis-4-aminocyclohexane-carboxylic acid ethyl ester hydrochloride;ETHYL (1R,4R)-4-AMINOCYCLOHEXANE-1-CARBOXYLATE HYDROCHLORIDE;trans-4-Aminocyclohexanecarboxylic Acid Ethyl Ester Hydrochloride;TRANS-4-AMINOCYCLOHEXANE CARBOXYLIC ACID ETHYL ESTER HYDROCHLORIDE

Chemical Property of trans-Ethyl 4-aminocyclohexanecarboxylate hydrochloride

Chemical Property:

• Melting Point: 153 °C
• PSA: 52.32000
• LogP: 2.56930
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 207.1026065
• Heavy Atom Count: 13
• Complexity: 151

Purity/Quality:

97% ^*data from raw suppliers

Ethyltrans-4-AminocyclohexanecarboxylateHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C1CCC(CC1)N.Cl
• Uses: Ethyl trans-4-Aminocyclohexanecarboxylate is a cyclohexane carboxylate amino isomer. Ethyl trans-4-Aminocyclohexanecarboxylate is used in the synthesis of trans-4-(6-substituted-9-purinyl)cyclohexylcarbinols as inhibitors of adenosine deaminase. trans-Ethyl 4-aminocyclohexanecarboxylate hydrochloride is a cyclohexane carboxylate amino isomer. Ethyl trans-4-Aminocyclohexanecarboxylate is used in the synthesis of trans-4-(6-substituted-9-purinyl)cyclohexylcarbinols as inhibitors of adenosine deaminase.

Technology Process of trans-Ethyl 4-aminocyclohexanecarboxylate hydrochloride

There total 15 articles about trans-Ethyl 4-aminocyclohexanecarboxylate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(1r,4r)-4-aminocyclohexanecarboxylic acid + ethanol (64-17-5) → (1r,4r)-ethyl 4-aminocyclohexanecarboxylate hydrochloride (2084-28-8,61367-17-7)

Guidance literature:

With hydrogenchloride; In water; at 60 ℃; for 20h;

Reference yield: 99.0%

(1r,4r)-4-aminocyclohexanecarboxylic acid + ethanol (64-17-5) → (1 r,4r)-ethyl 4-aminocyclohexanecarboxylate hydrochloride (2084-28-8,61367-17-7)

Guidance literature:

With hydrogenchloride; In ethanol; water; at 60 ℃; for 20h;

Reference yield: 96.0%

cis-4-aminocyclohexylcarboxylic acid + ethanol (64-17-5) → cis-ethyl 4-aminocyclohexanecarboxylate hydrochloride (2084-28-8,61367-17-7)

Guidance literature:

With hydrogenchloride; In water; at 60 ℃;

upstream raw materials:

ethyl 4-amino-1-cyclohexanecarboxylate

ethyl trans-4-aminocyclohexanecarboxylate

ethanol

trans-4-aminocyclohexanecarboxylic acid