(2,5-Dioxopyrrolidin-1-yl) 6-(3-phenylpropanoylamino)hexanoate

Base Information

• Chemical Name: (2,5-Dioxopyrrolidin-1-yl) 6-(3-phenylpropanoylamino)hexanoate
• CAS No.: 334616-48-7
• Molecular Formula: C19H24N2O5
• Molecular Weight: 360.41
• DSSTox Substance ID: DTXSID80398831
• Wikidata: Q82201037
• Mol file: 334616-48-7.mol

Synonyms:334616-48-7;N-Dihydrocinnamoylaminocaproic Acid, N-Hydroxysuccinimide Ester;(2,5-dioxopyrrolidin-1-yl) 6-(3-phenylpropanoylamino)hexanoate;N-Dihydrocinnamoylaminocaproic Acid N-Hydroxysuccinimide Ester;2,5-DIOXOPYRROLIDIN-1-YL 6-(3-PHENYLPROPANAMIDO)HEXANOATE;SCHEMBL2102802;DTXSID80398831;AKOS027447784;FT-0666920;J-019196;n-dihydrocinnamoyl aminocaproic acid n-hydroxysuccinimide ester;N-Dihydrocinnamoylaminocaproic acid,N-hydroxysuccinimide ester

Chemical Property of (2,5-Dioxopyrrolidin-1-yl) 6-(3-phenylpropanoylamino)hexanoate

Chemical Property:

• PSA: 96.27000
• LogP: 2.68120
• Solubility.: Chloroform, Dichloromethane, Ethyl Acetate,
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 11
• Exact Mass: 360.16852187
• Heavy Atom Count: 26
• Complexity: 498

Purity/Quality:

97% ^*data from raw suppliers

N-DihydrocinnamoylaminocaproicAcidN-HydroxysuccinimideEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CC(=O)N(C1=O)OC(=O)CCCCCNC(=O)CCC2=CC=CC=C2
• Uses: N-Dihydrocinnamoylaminocaproic Acid N-Hydroxysuccinimide Ester (cas# 334616-48-7) is a compound useful in organic synthesis.

Technology Process of (2,5-Dioxopyrrolidin-1-yl) 6-(3-phenylpropanoylamino)hexanoate

There total 1 articles about (2,5-Dioxopyrrolidin-1-yl) 6-(3-phenylpropanoylamino)hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

6-(3-phenylpropanamido)hexanoic acid (178622-38-3) + di(succinimido) carbonate (74124-79-1) → N-dihydrocinnamoylaminocaproic acid N-hydroxysuccinimide ester (334616-48-7)

Guidance literature:

With pyridine; In acetonitrile; at 20 ℃; for 2.5h;

Reference yield: 52.0%

N-dihydrocinnamoylaminocaproic acid N-hydroxysuccinimide ester (334616-48-7) + N-aminoethylcyclopamine (334616-31-8) → KAAD-Cyclopamine

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 1h;

upstream raw materials:

6-(3-phenylpropanamido)hexanoic acid

di(succinimido) carbonate

Refernces