3-Allyl-2-methoxybenzoic acid methyl ester

Base Information

• Chemical Name: 3-Allyl-2-methoxybenzoic acid methyl ester
• CAS No.: 75934-00-8
• Molecular Formula: C12H14O3
• Molecular Weight: 206.241
• Mol file: 75934-00-8.mol

Synonyms:3-Allyl-2-methoxybenzoic acid methyl ester

Chemical Property of 3-Allyl-2-methoxybenzoic acid methyl ester

Chemical Property:

• PSA: 35.53000
• LogP: 2.21030

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Allyl-2-methoxybenzoic acid methyl ester

There total 4 articles about 3-Allyl-2-methoxybenzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl salicylate (119-36-8,8024-54-2) → 2-Allyl-6-(carbomethoxy)anisole (75934-00-8)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 60 h

2: sodium hydride / 1) 20 min at 0 deg C 2) reflux for 12 h

With sodium hydride; potassium carbonate; In acetone;

DOI:10.1021/jo00317a027

Reference yield:

methyl 2-allyloxybenzoate (6282-42-4) → 2-Allyl-6-(carbomethoxy)anisole (75934-00-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 15 h / Heating

2: sodium hydride / 1) 20 min at 0 deg C 2) reflux for 12 h

With sodium hydride;

DOI:10.1021/jo00317a027

Reference yield:

methyl 3-allyl-salicylate (31456-98-1) + methyl iodide (74-88-4) → 2-Allyl-6-(carbomethoxy)anisole (75934-00-8)

Guidance literature:

With sodium hydride; Yield given. Multistep reaction; 1) 20 min at 0 deg C 2) reflux for 12 h;

DOI:10.1021/jo00317a027

upstream raw materials:

dimethyl sulfate

methyl 3-allyl-salicylate

methyl iodide

methyl 2-allyloxybenzoate

Downstream raw materials:

2,3-dihydro-1H-indole-7-carboxylic acid

2-<2-Methoxy-3-(2-hydroxyethyl)phenyl>-4,4-dimethyl-2-oxazoline

2-[3-(4,4-Dimethyl-4,5-dihydro-oxazol-2-yl)-2-methoxy-phenyl]-ethylamine

2-{2-[3-(4,4-Dimethyl-4,5-dihydro-oxazol-2-yl)-2-methoxy-phenyl]-ethyl}-isoindole-1,3-dione

Refernces