4-[(2-Methylpiperidin-1-yl)sulfonyl]aniline

Base Information

Chemical Name:4-[(2-Methylpiperidin-1-yl)sulfonyl]aniline
CAS No.:109099-69-6
Molecular Formula:C12H18N2O2S
Molecular Weight:254.353
Hs Code.:2935009090
DSSTox Substance ID:DTXSID90389396
Mol file:109099-69-6.mol

Synonyms:4-[(2-methylpiperidin-1-yl)sulfonyl]aniline;109099-69-6;4-(2-methylpiperidin-1-yl)sulfonylaniline;4-((2-Methylpiperidin-1-yl)sulfonyl)aniline;BAS 00631877;4-[(2-methylpiperidyl)sulfonyl]phenylamine;4-(2-Methyl-piperidine-1-sulfonyl)-phenylamine;TimTec1_000908;Oprea1_185989;Oprea1_811811;SCHEMBL23043835;DTXSID90389396;HMS1536J06;MFCD01055485;STK149448;AKOS000138504;AKOS016041767;NCGC00174994-01;LS-01154;CS-0315290;SR-01000310944;SR-01000310944-1;BRD-A88117712-001-01-1;4-[(2-methylpiperidin-1-yl)sulfonyl]aniline(SALTDATA: FREE)

Suppliers and Price of 4-[(2-Methylpiperidin-1-yl)sulfonyl]aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-[(2-Methylpiperidin-1-yl)sulfonyl]aniline
500mg
$ 240.00

Matrix Scientific
4-[(2-Methylpiperidin-1-yl)sulfonyl]aniline
500mg
$ 126.00

Crysdot
4-((2-Methylpiperidin-1-yl)sulfonyl)aniline 95+%
1g
$ 306.00

Chemenu
4-[(2-methylpiperidin-1-yl)sulfonyl]aniline 95%
10g
$ 960.00

Chemenu
4-[(2-methylpiperidin-1-yl)sulfonyl]aniline 95%
5g
$ 600.00

ChemBridge Corporation
4-[(2-methylpiperidin-1-yl)sulfonyl]aniline 95%
1 g
$ 185.00

American Custom Chemicals Corporation
4-(2-METHYL-PIPERIDINE-1-SULFONYL)-PHENYLAMINE 95.00%
5MG
$ 505.00

AK Scientific
4-[(2-Methylpiperidin-1-yl)sulfonyl]aniline
500mg
$ 220.00

Total 8 raw suppliers

Chemical Property of 4-[(2-Methylpiperidin-1-yl)sulfonyl]aniline

Chemical Property:

Melting Point:109-117 °C
Boiling Point:420.7±47.0 °C(Predicted)
PKA:2?+-.0.10(Predicted)
PSA：71.78000
Density:1.228±0.06 g/cm3(Predicted)
LogP:3.43180
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:254.10889899
Heavy Atom Count:17
Complexity:342

Purity/Quality:

97% ^*data from raw suppliers

4-[(2-Methylpiperidin-1-yl)sulfonyl]aniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCCCN1S(=O)(=O)C2=CC=C(C=C2)N

Technology Process of 4-[(2-Methylpiperidin-1-yl)sulfonyl]aniline

There total 4 articles about 4-[(2-Methylpiperidin-1-yl)sulfonyl]aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 346689-79-0
2-methyl-1-[(4-nitrophenyl)sulfonyl]piperidine

: 109099-69-6
4-((2-methylpiperidin-1-yl)sulfonyl)aniline

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethyl acetate; at 20 ℃; for 8h; under 3800.26 Torr;
DOI:10.1016/j.ejmech.2013.01.047

Reference yield:

: 121-60-8
p-acetylaminobenzenesulfonyl chloride

: 109-05-7,3000-79-1
2-Methylpiperidin

: 109099-69-6
4-((2-methylpiperidin-1-yl)sulfonyl)aniline

Guidance literature:: p-acetylaminobenzenesulfonyl chloride; 2-Methylpiperidin; With pyridine; at 20 - 100 ℃; Inert atmosphere;

With hydrogenchloride; In 1,4-dioxane; water; for 2h; Reflux; Inert atmosphere;

Reference yield:

: 109-05-7,3000-79-1
2-Methylpiperidin

: 109099-69-6
4-((2-methylpiperidin-1-yl)sulfonyl)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 20 °C

2: hydrogen; palladium 10% on activated carbon / ethyl acetate / 8 h / 20 °C / 3800.26 Torr

With palladium 10% on activated carbon; hydrogen; triethylamine; In dichloromethane; ethyl acetate;
DOI:10.1016/j.ejmech.2013.01.047