2-Methyl-1-(4-nitrophenylsulfonyl)piperidine

Base Information

Chemical Name:2-Methyl-1-(4-nitrophenylsulfonyl)piperidine
CAS No.:346689-79-0
Molecular Formula:C₁₂H₁₆N₂O₄S
Molecular Weight:284.336
Hs Code.:
DSSTox Substance ID:DTXSID401322780
ChEMBL ID:CHEMBL1447910

Synonyms:2-Methyl-1-(4-nitrophenylsulfonyl)piperidine;346689-79-0;2-methyl-1-((4-nitrophenyl)sulfonyl)piperidine;2-methyl-1-[(4-nitrophenyl)sulfonyl]piperidine;2-methyl-1-(4-nitrophenyl)sulfonylpiperidine;Cambridge id 5348376;2-Methyl-1-(4-nitro-benzenesulfonyl)-piperidine;Oprea1_623512;Oprea1_795826;MLS001207254;CHEMBL1447910;DTXSID401322780;HMS2823D19;STK077783;AKOS000524145;AKOS016294028;SMR000514063;VU0488295-1;AB00082009-01;Z45548666;F0306-0065

Suppliers and Price of 2-Methyl-1-(4-nitrophenylsulfonyl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-Methyl-1-(4-nitrophenylsulfonyl)piperidine

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:284.08307817
Heavy Atom Count:19
Complexity:418

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCCCN1S(=O)(=O)C2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of 2-Methyl-1-(4-nitrophenylsulfonyl)piperidine

There total 2 articles about 2-Methyl-1-(4-nitrophenylsulfonyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 109-05-7,3000-79-1
2-Methylpiperidin

: 346689-79-0
2-methyl-1-[(4-nitrophenyl)sulfonyl]piperidine

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃;
DOI:10.1016/j.ejmech.2013.01.047

Reference yield: 50.0%

: 109-06-8
α-picoline

: 542-91-6
H₂SiEt₂

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 346689-79-0
2-methyl-1-[(4-nitrophenyl)sulfonyl]piperidine

: 5-[diethylsilyl-2-methyl-1-(4-nitrophenylsulfonyl)]piperidine

Guidance literature:: α-picoline; H₂SiEt₂; With tris(pentafluorophenyl)borate; In toluene; at 85 ℃; for 18h; Inert atmosphere;

4-Nitrobenzenesulfonyl chloride; With dmap; triethylamine; In dichloromethane; at 23 ℃; for 12h; Inert atmosphere;
DOI:10.1021/jacs.5b09209

Reference yield: 97.0%

: 346689-79-0
2-methyl-1-[(4-nitrophenyl)sulfonyl]piperidine

: 109099-69-6
4-((2-methylpiperidin-1-yl)sulfonyl)aniline

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethyl acetate; at 20 ℃; for 8h; under 3800.26 Torr;
DOI:10.1016/j.ejmech.2013.01.047