BETA-OXO-4-METHOXY-BENZENEPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER

Base Information

Chemical Name:BETA-OXO-4-METHOXY-BENZENEPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER
CAS No.:54441-74-6
Molecular Formula:C14H18O4
Molecular Weight:250.295
Hs Code.:

Synonyms:BETA-OXO-4-METHOXY-BENZENEPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER

Suppliers and Price of BETA-OXO-4-METHOXY-BENZENEPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Acrotein
tert-Butylb-oxo-4-methoxybenzenepropanoate 97%
1g
$ 220.00

Total 2 raw suppliers

Chemical Property of BETA-OXO-4-METHOXY-BENZENEPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER

Chemical Property:

PSA：52.60000
LogP:2.60970

Purity/Quality:

95%-98% ^*data from raw suppliers

tert-Butylb-oxo-4-methoxybenzenepropanoate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of BETA-OXO-4-METHOXY-BENZENEPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER

There total 11 articles about BETA-OXO-4-METHOXY-BENZENEPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 540-88-5
acetic acid tert-butyl ester

: 52898-49-4
4,N-dimethoxy-N-methylbenzamide

: 54441-74-6
tert-butyl 3-(4-methoxyphenyl)-3-oxopropanoate

Guidance literature:: acetic acid tert-butyl ester; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

4,N-dimethoxy-N-methylbenzamide; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;
DOI:10.1002/ejoc.201300166

Reference yield:

: 100-07-2
4-methoxy-benzoyl chloride

: 54441-74-6
tert-butyl 3-(4-methoxyphenyl)-3-oxopropanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / dichloromethane / 2 h / 20 °C

2.1: n-butyllithium; diisopropylamine / hexane; tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

2.2: 1 h / -78 °C / Inert atmosphere

With n-butyllithium; triethylamine; diisopropylamine; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1002/ejoc.201300166