3-ForMyl-4-nitrophenyl boronicacid pinacol ester

Base Information

• Chemical Name: 3-ForMyl-4-nitrophenyl boronicacid pinacol ester
• CAS No.: 1184259-08-2
• Molecular Formula: C13H18BNO6
• Molecular Weight: 277.085
• Hs Code.: 2931900090
• Mol file: 1184259-08-2.mol

Synonyms:3-ForMyl-4-nitrophenyl boronicacid pinacol ester;2-Nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

Chemical Property of 3-ForMyl-4-nitrophenyl boronicacid pinacol ester

Chemical Property:

• PSA: 81.35000
• LogP: 2.22970
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

3-Formyl-4-ntrophenylboronicAcidPinacolEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-ForMyl-4-nitrophenyl boronicacid pinacol ester

There total 2 articles about 3-ForMyl-4-nitrophenyl boronicacid pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromo-2-nitrobenzaldehyde (5551-12-2) + bis(pinacol)diborane (73183-34-3) → 2-nitro-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzaldehyde (1184259-08-2)

Guidance literature:

With potassium acetate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tricyclohexylphosphine; In 1,4-dioxane; at 80 ℃; for 16.5h;

Reference yield:

5-bromo-2-nitrobenzaldehyde (20357-20-4) + bis(pinacol)diborane (73183-34-3) → 2-nitro-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzaldehyde (1184259-08-2)

Guidance literature:

With potassium acetate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tricyclohexylphosphine; In 1,4-dioxane; at 80 ℃; for 16h;

Reference yield:

N-[2-(2-bromo-phenyl)-ethyl]-benzenesulfonamide (1184254-68-9) + 2-nitro-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzaldehyde (1184259-08-2) → N-[2-(3'-formyl-4'-nitro-biphenyl-2-yl)-ethyl]-benzenesulfonamide (1184264-91-2)

Guidance literature:

With sodium carbonate; (bis(tricyclohexyl)phosphine)palladium(II) dichloride; In 1,2-dimethoxyethane; water; at 80 ℃; for 3h;

upstream raw materials:

4-bromo-2-nitrobenzaldehyde

bis(pinacol)diborane

5-bromo-2-nitrobenzaldehyde

Downstream raw materials:

N-[2-(3'-formyl-4'-nitro-biphenyl-2-yl)-ethyl]-benzenesulfonamide