Peduncularine

Base Information

Chemical Name:Peduncularine
CAS No.:34964-75-5
Molecular Formula:C20H24N2
Molecular Weight:292.42
Hs Code.:
Mol file:34964-75-5.mol

Synonyms:

Suppliers and Price of Peduncularine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Peduncularine

Chemical Property:

PSA：19.03000
LogP:4.24180

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Peduncularine

There total 35 articles about Peduncularine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 119184-36-0
(1S,5R,7R)-6-isopropyl-8-methylene-7-<3,3-(trimethylenedioxy)-propyl>-6-azabicyclo<3.2.1>-3-octene

: 100-63-0
phenylhydrazine

: 34964-75-5
Peduncularine

Guidance literature:: With sulfuric acid; In water; for 17h; Heating;
DOI:10.1021/ja00189a036

Reference yield:

: 111097-61-1,111097-62-2
(4S,5RS)-5-ethoxy-4-hydroxy-1-isopropyl-2-pyrrolidinone

: 34964-75-5
Peduncularine

Guidance literature:: Multi-step reaction with 13 steps

1: 1.) (i-Pr)2NLi / 1.) - 78 deg C; -25 -> -20 deg C, 1h, 2.) - 117 deg C, 6 h; room temp., 40 h

2: 1.) HCO₂H, 2.) NH₃/MeOH / 1.) room temp., 3 h, 2.) room temp., 18 h

3: 97 percent / 1.) O₃ / 1.) CH₂Cl₂, - 78 deg C, 2.) dimethyl sulfide, room temp., 17 h

4: 57 percent / NaBH₄ / ethanol / 1 h / Ambient temperature

5: 91 percent / 4-(dimethylamino)pyridine / pyridine / 19 h / Ambient temperature

6: 54 percent / 600 °C / 0.05 Torr

7: 83 percent / NaOEt / ethanol / 0.75 h / Ambient temperature

8: 96 percent / 1.) oxalyl chloride, DMSO, 2.) Et₃N / CH₂Cl₂, 1.) -60 deg C, 1 h, 2.) room temp., 20 h

9: 1.) n-BuLi / 1.) THF, hexane, 25 min, room temp., 2.) reflux, 16 h

10: 95 percent / Lawesson's reagent / toluene / 5 h / Heating

11: 92 percent / diethyl ether / 18 h

12: 2.) NaBH₃CN / 1.) CH₂Cl₂, THF -78 -> 0 deg C, 40 min; 0 -> 20 deg C, 90 min, 2.) AcOH, 1.5 h

13: 44 percent / H₂SO₄ / H₂O / 17 h / Heating

With Lawessons reagent; methanol; dmap; sodium tetrahydroborate; n-butyllithium; formic acid; oxalyl dichloride; sulfuric acid; ammonia; sodium ethanolate; sodium cyanoborohydride; ozone; dimethyl sulfoxide; triethylamine; lithium diisopropyl amide; In pyridine; diethyl ether; ethanol; water; toluene;
DOI:10.1021/ja00189a036

Reference yield:

: 111097-58-6
(S)-acetoxy-1-isopropylsuccinimide

: 34964-75-5
Peduncularine

Guidance literature:: Multi-step reaction with 15 steps

1: 1.) NaBH₄, 2.) 1 M H₂SO₄ / 1.) - 15 deg C, 15 min, 2.) room temp., 1 h

2: 99 percent / NaOEt / ethanol / 1.5 h / Ambient temperature

3: 1.) (i-Pr)2NLi / 1.) - 78 deg C; -25 -> -20 deg C, 1h, 2.) - 117 deg C, 6 h; room temp., 40 h

4: 1.) HCO₂H, 2.) NH₃/MeOH / 1.) room temp., 3 h, 2.) room temp., 18 h

5: 97 percent / 1.) O₃ / 1.) CH₂Cl₂, - 78 deg C, 2.) dimethyl sulfide, room temp., 17 h

6: 57 percent / NaBH₄ / ethanol / 1 h / Ambient temperature

7: 91 percent / 4-(dimethylamino)pyridine / pyridine / 19 h / Ambient temperature

8: 54 percent / 600 °C / 0.05 Torr

9: 83 percent / NaOEt / ethanol / 0.75 h / Ambient temperature

10: 96 percent / 1.) oxalyl chloride, DMSO, 2.) Et₃N / CH₂Cl₂, 1.) -60 deg C, 1 h, 2.) room temp., 20 h

11: 1.) n-BuLi / 1.) THF, hexane, 25 min, room temp., 2.) reflux, 16 h

12: 95 percent / Lawesson's reagent / toluene / 5 h / Heating

13: 92 percent / diethyl ether / 18 h

14: 2.) NaBH₃CN / 1.) CH₂Cl₂, THF -78 -> 0 deg C, 40 min; 0 -> 20 deg C, 90 min, 2.) AcOH, 1.5 h

15: 44 percent / H₂SO₄ / H₂O / 17 h / Heating

With Lawessons reagent; methanol; dmap; sodium tetrahydroborate; n-butyllithium; formic acid; oxalyl dichloride; sulfuric acid; ammonia; sodium ethanolate; sodium cyanoborohydride; ozone; dimethyl sulfoxide; triethylamine; lithium diisopropyl amide; In pyridine; diethyl ether; ethanol; water; toluene;
DOI:10.1021/ja00189a036