2-CyclopropylMorpholine

Base Information

• Chemical Name: 2-CyclopropylMorpholine
• CAS No.: 1063734-79-1
• Molecular Formula: C7H13NO
• Molecular Weight: 127.18422
• Hs Code.: 2934999090
• Mol file: 1063734-79-1.mol

Synonyms:2-CyclopropylMorpholine;2-Cyclopropyl-morpholine HCl

Chemical Property of 2-CyclopropylMorpholine

Chemical Property:

• PSA: 21.26000
• LogP: 0.71360
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

2-Cyclopropyl-morpholine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-CyclopropylMorpholine

There total 4 articles about 2-CyclopropylMorpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-cyclopropylmorpholin-3-one → 2-cyclopropylmorpholine (1063734-79-1)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 6h; Reflux;

Reference yield:

2-cyclopropyl-2-hydroxyacetonitrile (5648-87-3) → 2-cyclopropylmorpholine (1063734-79-1)

Guidance literature:

Multi-step reaction with 4 steps

1: lithium aluminium tetrahydride / 20 °C

2: pyridine / dichloromethane / 2 h / 0 °C

3: potassium carbonate / toluene / 18 h / Reflux

4: lithium aluminium tetrahydride / tetrahydrofuran / 6 h / Reflux

With pyridine; lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; dichloromethane; toluene;

Reference yield:

2-amino-(1RS)-1-cyclopropylethanol (54120-02-4) → 2-cyclopropylmorpholine (1063734-79-1)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine / dichloromethane / 2 h / 0 °C

2: potassium carbonate / toluene / 18 h / Reflux

3: lithium aluminium tetrahydride / tetrahydrofuran / 6 h / Reflux

With pyridine; lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; dichloromethane; toluene;

upstream raw materials:

2-cyclopropyl-2-hydroxyacetonitrile

2-amino-(1RS)-1-cyclopropylethanol

Refernces