4-(4-CHLOROPHENYL)-4-HYDROXY-A,A-DIPHENYL-1-PIPERIDINEPENTANENITRILE HYDROCHLORIDE

Base Information

Chemical Name:4-(4-CHLOROPHENYL)-4-HYDROXY-A,A-DIPHENYL-1-PIPERIDINEPENTANENITRILE HYDROCHLORIDE
CAS No.:193542-65-3
Molecular Formula:C28H30Cl2N2O
Molecular Weight:445.004
Hs Code.:
Mol file:193542-65-3.mol

Synonyms:4-(4-CHLOROPHENYL)-4-HYDROXY-A,A-DIPHENYL-1-PIPERIDINEPENTANENITRILE HYDROCHLORIDE;BX 513 HYDROCHLORIDE;4-(4-Chlorophenyl)-4-hydroxy-α,α-diphenyl-1-piperidinepentanenitrilehydrochloride

Suppliers and Price of 4-(4-CHLOROPHENYL)-4-HYDROXY-A,A-DIPHENYL-1-PIPERIDINEPENTANENITRILE HYDROCHLORIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
BX 513 hydrochloride
10mg
$ 480.00

Tocris
BX513hydrochloride ≥99%(HPLC)
10
$ 227.00

Tocris
BX513hydrochloride ≥99%(HPLC)
50
$ 924.00

DC Chemicals
BX-513hydrochloride >98%
100 mg
$ 450.00

Crysdot
5-(4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl)-2,2-diphenylpentanenitrile 95%
100mg
$ 780.00

American Custom Chemicals Corporation
4-(4-CHLOROPHENYL)-4-HYDROXY-ALPHA,ALPHA-DIPHENYL-1-PIPERIDINEPENTANENITRILE HYDROCHLORIDE 95.00%
5MG
$ 502.91

Alichem
5-(4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl)-2,2-diphenylpentanenitrile
100mg
$ 834.60

Total 10 raw suppliers

Chemical Property of 4-(4-CHLOROPHENYL)-4-HYDROXY-A,A-DIPHENYL-1-PIPERIDINEPENTANENITRILE HYDROCHLORIDE

Chemical Property:

PSA：47.26000
LogP:6.65338
Storage Temp.:Desiccate at +4°C

Purity/Quality:

≥95% ^*data from raw suppliers

BX 513 hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-(4-CHLOROPHENYL)-4-HYDROXY-A,A-DIPHENYL-1-PIPERIDINEPENTANENITRILE HYDROCHLORIDE

There total 5 articles about 4-(4-CHLOROPHENYL)-4-HYDROXY-A,A-DIPHENYL-1-PIPERIDINEPENTANENITRILE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 39512-49-7
4-(4-chlorophenyl)-4-hydroxypiperidine

: 14078-27-4
α-(3-bromopropyl)-α-phenyl-benzeneacetonitrile

: 193542-65-3
5-[4-(4-chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentanenitrile

Guidance literature:: With sodium carbonate; sodium iodide; In acetonitrile; Heating;
DOI:10.1021/jm050418d

Reference yield:

: 86-29-3
Diphenylacetonitrile

: 193542-65-3
5-[4-(4-chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentanenitrile

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH / dimethylformamide / 0 °C

1.2: dimethylformamide

2.1: 78 percent / NaI; Na₂CO₃ / acetonitrile / Heating

With sodium hydride; sodium carbonate; sodium iodide; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm050418d