2-(1,3-dihydro-2H-isoindol-2-yl)ethanol

Base Information

Chemical Name:2-(1,3-dihydro-2H-isoindol-2-yl)ethanol
CAS No.:57944-79-3
Molecular Formula:C₁₀H₁₃NO
Molecular Weight:163.219
Hs Code.:2933990090
DSSTox Substance ID:DTXSID70482415
Nikkaji Number:J2.211.118C
Wikidata:Q82318700
Mol file:57944-79-3.mol

Synonyms:57944-79-3;2,3-Dihydro-1H-isoindole-2-ethanol;2-(1,3-dihydro-2H-isoindol-2-yl)ethanol;2-(1,3-dihydroisoindol-2-yl)ethanol;2-(2,3-dihydro-1H-isoindol-2-yl)ethan-1-ol;SCHEMBL377728;2-(2-hydroxyethyl) isoindoline;DTXSID70482415;RPYLGKKUWYIZNY-UHFFFAOYSA-N;AKOS004121653;CS-0264175;EN300-92229

Suppliers and Price of 2-(1,3-dihydro-2H-isoindol-2-yl)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(2,3-DIHYDRO-1H-ISOINDOL-2-YL)ETHAN-1-OL 95.00%
5MG
$ 498.78

Total 3 raw suppliers

Chemical Property of 2-(1,3-dihydro-2H-isoindol-2-yl)ethanol

Chemical Property:

Vapor Pressure:0.002mmHg at 25°C
Boiling Point:275.797°C at 760 mmHg
PKA:14.65±0.10(Predicted)
Flash Point:136.621°C
PSA：23.47000
Density:1.128g/cm³
LogP:0.93240
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:163.099714038
Heavy Atom Count:12
Complexity:135

Purity/Quality:

99% ^*data from raw suppliers

2-(2,3-DIHYDRO-1H-ISOINDOL-2-YL)ETHAN-1-OL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C2=CC=CC=C2CN1CCO

Technology Process of 2-(1,3-dihydro-2H-isoindol-2-yl)ethanol

There total 5 articles about 2-(1,3-dihydro-2H-isoindol-2-yl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 363165-74-6
methyl 2-(1,3-dihydroisoindol-2-yl)acetate

: 57944-79-3
N-(2-hydroxyethyl)isoindoline

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; for 2h; Heating;
DOI:10.1016/j.tetlet.2005.06.118

Reference yield:

: 496-12-8
isoindoline

: 540-51-2
2-bromoethanol

: 57944-79-3
N-(2-hydroxyethyl)isoindoline

Guidance literature:: With triethylamine; In ethyl acetate; toluene;

Reference yield:

: 91-13-4
α,α'-dibromo-o-xylene

: 57944-79-3
N-(2-hydroxyethyl)isoindoline

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / potassium carbonate / acetonitrile / 14 h / Heating

2: 94 percent / lithium aluminum hydride / diethyl ether; tetrahydrofuran / 2 h / Heating

With lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; diethyl ether; acetonitrile;
DOI:10.1016/j.tetlet.2005.06.118