(R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate

Base Information

Chemical Name:(R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate
CAS No.:1234321-83-5
Molecular Formula:C13H14F3NO3
Molecular Weight:289.254
Hs Code.:2924299090
Mol file:1234321-83-5.mol

Synonyms:(R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate;Methyl (R)-3-acetamido-4-(2,4,5-trifluorophenyl)butanoate

Suppliers and Price of (R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
methyl(R)-3-acetamido-4-(2,4,5-trifluorophenyl)butanoate 95%
1g
$ 282.00

American Custom Chemicals Corporation
(R)-METHYL-3-ACETAMIDO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOATE 95.00%
1G
$ 675.15

American Custom Chemicals Corporation
(R)-METHYL-3-ACETAMIDO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOATE 95.00%
5MG
$ 501.79

Alichem
(R)-Methyl3-acetamido-4-(2,4,5-trifluorophenyl)butanoate
1g
$ 400.00

Total 15 raw suppliers

Chemical Property of (R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate

Chemical Property:

Boiling Point:431.7±45.0 °C(Predicted)
PKA:14.81±0.46(Predicted)
PSA：58.89000
Density:1.273±0.06 g/cm3(Predicted)
LogP:2.55450
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

methyl(R)-3-acetamido-4-(2,4,5-trifluorophenyl)butanoate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate

There total 4 articles about (R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1234321-81-3
(Z)-3-acetylamino-4-(2,4,5-trifluorophenyl)-2-butenoic acid methyl ester

: 1234321-83-5
(R)-methyl-3-N-acetylamino-4-(2,4,5-trifluorophenyl)butanoate

Guidance literature:: With hydrogen; TangPhosRh(COD) BF₄; In tetrahydrofuran; at 20 ℃; for 18h; under 7500.75 Torr;

Reference yield:

: 209995-38-0
(2,4,5-trifluorophenyl)acetic acid

: 1234321-83-5
(R)-methyl-3-N-acetylamino-4-(2,4,5-trifluorophenyl)butanoate

Guidance literature:: Multi-step reaction with 4 steps

1.1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 3 h / 0 - 20 °C

1.2: 16 h / 20 °C

2.1: 4 h / 60 °C

2.2: 10 h / 60 °C

3.1: pyridine / tetrahydrofuran / 20 h / Reflux

4.1: hydrogen; bis(norbornadiene)rhodium(l)tetrafluoroborate; MeO-BIBOP / methanol / 36 h / 20 °C / 7500.75 Torr

With pyridine; bis(norbornadiene)rhodium(l)tetrafluoroborate; hydrogen; MeO-BIBOP; 1,1'-carbonyldiimidazole; In tetrahydrofuran; methanol;

Reference yield:

: 764667-64-3
5-(1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione

: 1234321-83-5
(R)-methyl-3-N-acetylamino-4-(2,4,5-trifluorophenyl)butanoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: 4 h / 60 °C

1.2: 10 h / 60 °C

2.1: pyridine / tetrahydrofuran / 20 h / Reflux

3.1: hydrogen; bis(norbornadiene)rhodium(l)tetrafluoroborate; MeO-BIBOP / methanol / 36 h / 20 °C / 7500.75 Torr

With pyridine; bis(norbornadiene)rhodium(l)tetrafluoroborate; hydrogen; MeO-BIBOP; In tetrahydrofuran; methanol;